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23687-26-5

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23687-26-5 Usage

Description

6-Aminoisoquinoline is an organic compound with the molecular formula C9H8N2. It is a heterocyclic compound featuring a quinoline ring with an amino group at the 6th position. 6-Aminoisoquinoline serves as a key intermediate in the synthesis of various pharmaceuticals and chemical compounds due to its unique structure and reactivity.

Uses

Used in Pharmaceutical Industry:
6-Aminoisoquinoline is used as a reactant for the preparation of N-[2-(4-methylpiperidin-1-yl)-6-(trifluoromethyl)-pyridin-3-ylmethyl] N''-(6,6-fused heterocyclic) ureas. These compounds are highly potent TRPV1 antagonists, which are valuable in the development of medications targeting pain relief and other conditions associated with the transient receptor potential vanilloid 1 (TRPV1) receptor. The antagonistic action on TRPV1 can help in managing pain, inflammation, and thermal hyperalgesia.

Check Digit Verification of cas no

The CAS Registry Mumber 23687-26-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,6,8 and 7 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 23687-26:
(7*2)+(6*3)+(5*6)+(4*8)+(3*7)+(2*2)+(1*6)=125
125 % 10 = 5
So 23687-26-5 is a valid CAS Registry Number.
InChI:InChI=1/C9H8N2/c10-9-2-1-8-6-11-4-3-7(8)5-9/h1-6H,10H2

23687-26-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name isoquinolin-6-amine

1.2 Other means of identification

Product number -
Other names Isoquinoline,6-amino

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:23687-26-5 SDS

23687-26-5Relevant articles and documents

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Brown,Mitchell

, p. 1053 (1972)

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Methods for the preparation of 6-aminoisoquinoline

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Page/Page column 21; 22, (2018/01/21)

Described are methods for the preparation of 6-aminoisoquinoline, a useful intermediate compound in the synthesis of kinase inhibitors.

NOVEL SELECTIVE ANDROGEN RECEPTOR MODULATORS

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Page/Page column, (2014/06/23)

The present invention relates to a compound of Formula 1, 2 or 3: wherein A is N or —CR0—, where R0 is hydrogen, C1-C6 linear or branched chain alkyl, etc., Z is —CRe—, or, —N—, where Re is hydrogen, C1-C6 linear or branched chain alkyl,etc.; R1 is hydrogen, C1-C6 linear or branched chain alkyl, etc.; R2 are independently hydrogen or C1-C6 linear or branched chain alkyl; R3 and R4 are independently hydrogen, C1-C6 linear or branched chain alkyl, etc.;. R5 and R6 are independently hydrogen or C1-C6 linear or branched chain alkyl, etc.; R8 is hydrogen, C1-C6 linear or branched chain alkyl, etc.; R9 and R10 are independently hydrogen or C1-C6 linear or branched chain alkyl, etc.; Q is —CO—, —(CH2)q—, —(CHRs)q—, or (CRsRt)q—, where Rs and Rt are independently C1-C6 linear or branched chain alkyl, aryl, alkylaryl, heteroaryl or alkylheteroaryl; where q is 0, 1, 2, or 3; and, where n is 0, 1, 2, 3, 4 or 5; or, a pharmaceutically acceptable salt thereof, to compositions containing such compounds; and to the uses of such compounds in the treatment of various diseases, particularly, those affected or mediated by the androgen receptor.

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