23706-99-2

Basic information

• Product Name: 1H-Indazole-3-carboxamide, N-phenyl-
• CAS NO: 23706-99-2
• Molecular Formula: C14H11N3O
• Molecular Weight: 237.261
• Mol File: 23706-99-2.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 1H-Indazole-3-carboxamide, N-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indazole-3-carboxamide, N-phenyl-(23706-99-2)
• EPA Substance Registry System: 1H-Indazole-3-carboxamide, N-phenyl-(23706-99-2)

Safety Data

• Hazardous Substances Data: 23706-99-2(Hazardous Substances Data)

Usage

Structure

A derivative of indazole with a phenyl group attached to the nitrogen atom

Usage

Building block for the synthesis of biologically active compounds in the pharmaceutical industry

Potential activities

Antitumor and antioxidant

Therapeutic applications

Being researched for potential applications

Other uses

Intermediate in the production of dyes, pigments, and other organic compounds

Precautions

Potential hazards and adverse effects if not handled properly

Upstream product

• 62-53-3 aniline 
• 4498-67-3 1H-Indazole-3-carboxylic acid 
• 72083-74-0 1H-indazole-3-carbonyl chloride 

Downstream Products

• 1325682-04-9 1-(pyridine-4-carbonyl)-1H-indazole-3-carboxylic acid phenylamide 
• 1325682-75-4 1-(4-chlorophenyl)-1H-indazole-3-carboxylic acid phenylamide 
• 1325681-98-8 1-(4-fluorobenzoyl)-1H-indazole-3-carboxylic acid phenylamide 
• 1325681-89-7 1-(3-chlorobenzoyl)-1H-indazole-3-carboxylic acid phenylamide 
• 1325681-87-5 1-(2-chlorobenzoyl)-1H-indazole-3-carboxylic acid phenylamide 
• 1325681-80-8 1-benzoyl-1H-indazole-3-carboxylic acid phenylamide 
• 1325681-85-3 1-(4-methylbenzoyl)-1H-indazole-3-carboxylic acid phenylamide 
• 1325682-74-3 1-(4-chlorobenzyl)-1H-indazole-3-carboxylic acid phenylamide 
• 1325681-95-5 1-(4-nitrobenzoyl)-1H-indazole-3-carboxylic acid phenylamide 
• 1325681-81-9 1-(2-methylbenzoyl)-1H-indazole-3-carboxylic acid phenylamide 
• 1325682-73-2 1-(4-chlorobenzenesulfonyl)-1H-indazole-3-carboxylic acid phenylamide 
• 1325682-72-1 1-(toluene-4-sulfonyl)-1H-indazole-3-carboxylic acid phenylamide 
• 1325681-97-7 1-(3-fluorobenzoyl)-1H-indazole-3-carboxylic acid phenylamide 
• 1449714-17-3 1-(3-benzamidobenzyl)-N-phenyl-1H-indazole-3-carboxamide 

Relevant articles and documents

Preparation methods of 1H-indazol-3-carboxylic acid derivative, granisetron and lonidamine

The invention relates to preparation methods of a 1H-indazol-3-carboxylic acid derivative, granisetron and lonidamine. The 1H-indazol-3-carboxylic acid derivative is a compound with a structure shown in a formula (1) and a formula (2), and is mainly structurally characterized by having a 1H-indazol-3-carboxylic acid amide skeleton and a 1H-indazol-3-carboxylic ester skeleton. The 1H-indazol-3-carboxylic acid derivative can be synthesized by taking simple o-aminophenylacetic acid amide or o-aminophenylacetic acid ester as an initial raw material. The 1H-indazol-3-carboxylic acid derivative is a key intermediate for synthesizing a plurality of medicines, such as granisetron, lonidamine and the like. The synthesis method of the 1H-indazol-3-carboxylic acid derivative and the drug molecules glassetron and lonidamine is simple, the reaction condition is mild, the reaction speed is high, the yield is high, and purification is easy.

1 - (3 - benzoyl-aminobenzyl) - 1H - indazole - 3 - carboxamides and its preparation method and anti-viral uses (by machine translation)

The invention relates to a anti-viral inhibitors, in particular, relates to a class of non-nucleoside anti-virus can be used as an inhibitor of the general formula 1 indicated by the 1 - (3 - benzoyl-aminobenzyl) - 1H - indazole - 3 - carboxamides of the organic small molecule compound, and its pharmaceutically acceptable salt or hydrate, its preparation method and its in preparation for treating hepatitis c, hepatitis b, influenza, herpes, viral diseases such as aids in the application of the pharmaceutical, in particular for the preparation of a medicament in the treatment of hepatitis c of the application. Said compound of the invention has the advantages of simple synthesis, easy availability of raw materials, the advantages of low toxicity. (by machine translation)

Synthesis and HepatitisC Antiviral Activity of 1-Aminobenzyl-1H-indazole-3-carboxamide Analogues

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