23780-13-4

Basic information

• Product Name: (2-PHENYL-1,3-THIAZOL-4-YL)METHANOL
• Synonyms: (2-PHENYL-THIAZOL-4-YL)-METHANOL;(2-PHENYL-1,3-THIAZOL-4-YL)METHANOL;4-(HYDROXYMETHYL)-2-PHENYLTHIAZOLE;RARECHEM AL BD 1318;4-(Hydroxymethyl)-2-phenyl-1,3-thiazole;4-ThiazoleMethanol, 2-phenyl-
• CAS NO: 23780-13-4
• Molecular Formula: C₁₀H₉NOS
• Molecular Weight: 191.25
• Mol File: 23780-13-4.mol
• Article Data: 16

Chemical Properties

• Melting Point: 65 °C
• Boiling Point: 372.2 °C at 760 mmHg
• Flash Point: 178.9 °C
• Appearance: /
• Density: 1.264 g/cm³
• Vapor Pressure: 3.37E-06mmHg at 25°C
• Refractive Index: 1.629
• PKA: 13.14±0.10(Predicted)
• CAS DataBase Reference: (2-PHENYL-1,3-THIAZOL-4-YL)METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (2-PHENYL-1,3-THIAZOL-4-YL)METHANOL(23780-13-4)
• EPA Substance Registry System: (2-PHENYL-1,3-THIAZOL-4-YL)METHANOL(23780-13-4)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 24/25-41-37/38-22
• Safety Statements: 22-36/37/39-39-26
• Hazardous Substances Data: 23780-13-4(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Tetrahedron Letters, 10, p. 2797, 1969 DOI: 10.1017/S0009838800024678

InChI:InChI=1/C10H9NOS/c12-6-9-7-13-10(11-9)8-4-2-1-3-5-8/h1-5,7,12H,6H2

Upstream product

• 4771-31-7 2-phenyl-4-chloromethylthiazole 
• 59937-01-8 2-phenylthiazole-4-carboxylic acid ethyl ester 
• 2227-79-4 benzenecarbothioamide 
• 854473-16-8 acetic acid-(2-phenyl-thiazol-4-ylmethyl ester) 
• 100-47-0 benzonitrile 
• 6704-31-0 oxetan-3-one 
• 7113-02-2 2-phenyl-1,3-thiazole-4-carboxylic acid methyl ester 
• 55-21-0 benzamide 

Downstream Products

• 7113-10-2 2-phenyl-1,3-thiazole-4-carboxylic acid 
• 21160-54-3 (5-bromo-2-phenyl-thiazol-4-yl)-methanol 
• 20949-81-9 2-phenyl-thiazole-4-carbaldehyde 
• 3474-90-6 (E)-3-(2-phenylthiazol-4-yl)propenoic acid 
• 857550-21-1 2-phenyl-1,3-thiazole-4-carboxamide 
• 36094-04-9 2-phenyl-1,3-thiazole-4-carboxylic acid chloride 
• 20949-91-1 5-bromo-2-phenylthiazole-4-carbaldehyde 
• 21160-52-1 5-bromo-2-phenyl-thiazole-4-carboxylic acid 
• 1244030-71-4 2-amino-3-cyano-7-(dimethylamino)-4-(2-phenylthiazol-4-yl)-4H-chromene 
• 1476848-13-1 1-(6-fluoro-4-((2-phenylthiazol-4-yl)methoxy)benzofuran-2-yl)ethanone 
• 1476848-14-2 2-bromo-1-(6-fluoro-4-((2-phenylthiazol-4-yl)methoxy)benzofuran-2-yl)ethanone 
• 1476848-16-4 6-(6-Chloro-4-((2-phenylthiazol-4-yl)methoxy)benzofuran-2-yl)-2-methoxyimidazo[2,1-b][1,3,4]thiadiazole 
• 1476848-26-6 2-Methoxy-6-(4-((2-phenylthiazol-4-yl)methoxy)benzofuran-2-yl)imidazo[2,1-b][1,3,4]thiadiazole 
• 1476848-35-7 (S)-2-(1-Fluoroethyl)-6-(6-methoxy-4-((2-phenylthiazol-4-yl)methoxy)benzofuran-2-yl)imidazo[2,1-b][1,3,4]thiadiazole 

Relevant articles and documents

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Synthesis of new 2-(thiazol-4-yl)thiazolidin-4-one derivatives as potential anti-mycobacterial agents

To search for potent antimycobacterial lead compounds, a new series of 3-substituted phenyl-2-(2-(substituted phenyl)thiazol-4-yl) thiazolidin-4-one (5a-t) derivatives have been synthesized by the condensation of 2-substituted phenyl thiazole-4-carbaldehy

I2/TBHP-Mediated tandem cyclization and oxidation reaction: Facile access to 2-substituted thiazoles and benzothiazoles

The efficient synthesis of 2-substituted thiazoles and benzothiazoles has been accomplished employing readily available cysteine esters and 2-aminobenzenethiols as N and S sources. The reaction proceeds under an I2/TBHP system and involves a on