23786-93-8 Usage
Description
1,1-Diethoxycyclopentane is an organic compound with the molecular formula C7H14O2. It is a colorless liquid that is soluble in water and has a mild odor. It is a reagent used in the synthesis of various compounds, particularly in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
1,1-Diethoxycyclopentane is used as a reagent for the synthesis of Quinbolone (Q670150), which is a cyclopentenyl ether derivative of Boldenone (B675100) and also its active metabolite. Quinbolone exhibits weak androgenic activity, making it a potential candidate for therapeutic applications in conditions related to androgen deficiency or imbalance.
In the synthesis of Quinbolone, 1,1-diethoxycyclopentane serves as a key intermediate, contributing to the formation of the cyclopentenyl ether structure that is characteristic of this class of compounds. The weak androgenic activity of Quinbolone suggests that it may have potential applications in the treatment of conditions such as male hypogonadism, where androgen replacement therapy is indicated.
Furthermore, the use of 1,1-diethoxycyclopentane in the synthesis of Quinbolone highlights its importance in the development of novel therapeutic agents with potential applications in various medical fields. As research continues to explore the properties and potential uses of this compound, it is likely that additional applications will be discovered, further expanding the utility of 1,1-diethoxycyclopentane in the pharmaceutical industry.
Synthesis Reference(s)
Tetrahedron Letters, 32, p. 2429, 1991 DOI: 10.1016/S0040-4039(00)74345-0
Check Digit Verification of cas no
The CAS Registry Mumber 23786-93-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,7,8 and 6 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 23786-93:
(7*2)+(6*3)+(5*7)+(4*8)+(3*6)+(2*9)+(1*3)=138
138 % 10 = 8
So 23786-93-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H18O2/c1-3-10-9(11-4-2)7-5-6-8-9/h3-8H2,1-2H3
23786-93-8Relevant articles and documents
2,3-dichloro-5,6-dicyano-p-benzoquinone (DDQ) as a highly efficient and mild catalyst for diethyl acetalization of carbonyl compounds
Karimi, Babak,Ashtiani, Ashraf Miri
, p. 1199 - 1200 (1999)
Various types of structurally different carbonyl compounds in the presence of ethyl orthoformate (EtO)3CH could be efficiently converted to their diethyl acetals by using a catalytic amount (1-3 mol%) of DDQ under mild reaction conditions.
Highly regioselective synthesis of trifluoromethyl derivatives of pyrazolo[1,5-a]pyrimidines bearing fused cycloalkane rings using (2-ethoxycycloalkenyl)-2,2,2-trifluoroethanones
Emelina, Elena E.,Petrov, Aleksander A.,Selivanov, Stanislav I.,Nelyubina, Yulia V.,Antipin, Mikhail Yu.
experimental part, p. 861 - 869 (2009/12/30)
8-Trifluoromethyl-6,7-dihydro-5H-1,4,8a-triaza-s-indacene and 9-trifluoromethyl-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazolines were efficiently generated by condensation of 5(3)-aminopyrazoles with (2-ethoxycycloalkenyl)-2,2,2-trifluoroethanones and isolated in excellent yields. The regiochemistry of the prepared compounds was established by 1H, 13C and 19F NMR spectroscopy and X-ray diffraction analysis.
Bronsted acidic ionic liquids as efficient and recyclable catalysts for protection of carbonyls to acetals and ketals under mild conditions
Du, Yuying,Tian, Fuli
, p. 2703 - 2708 (2007/10/03)
A series of acidic ionic liquids have been used as efficient catalysts for the protection of various carbonyl compounds at room temperature. The features of mild conditions, satisfactory isolated yield, simple workup, and the recyclability of the catalyst were present in this process. Copyright Taylor & Francis, Inc.
