23815-87-4

Basic information

• Product Name: H-ARG-PRO-PRO-GLY-PHE-SER-PRO-OH ACETATE SALT
• Synonyms: H-ARG-PRO-PRO-GLY-PHE-SER-PRO-OH ACETATE SALT;H-ARG-PRO-PRO-GLY-PHE-SER-PRO-OH ACOH;ARG-PRO-PRO-GLY-PHE-SER-PRO;ARG-PRO-PRO-GLY-PHE-SER-PRO ACETATE;BRADYKININ FRAGMENT 1-7;BRADYKININ (1-7);BRADYKININ 1-7 ACETATE;RPPGFSP
• CAS NO: 23815-87-4
• Molecular Formula: C35H52N10O9
• Molecular Weight: 756.86
• Product Categories: Peptide;Bradykinins;Peptides and Proteins;Peptides for Cell Biology
• Mol File: 23815-87-4.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Density: 1.52 g/cm³
• Refractive Index: 1.695
• Storage Temp.: −20°C
• Water Solubility: Soluble in water (1 mg/ml).
• CAS DataBase Reference: H-ARG-PRO-PRO-GLY-PHE-SER-PRO-OH ACETATE SALT(CAS DataBase Reference)
• NIST Chemistry Reference: H-ARG-PRO-PRO-GLY-PHE-SER-PRO-OH ACETATE SALT(23815-87-4)
• EPA Substance Registry System: H-ARG-PRO-PRO-GLY-PHE-SER-PRO-OH ACETATE SALT(23815-87-4)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 23815-87-4(Hazardous Substances Data)

Usage

Description

H-ARG-PRO-PRO-GLY-PHE-SER-PRO-OH ACETATE SALT, also known as Bradykinin Fragment 1-7, is a peptide derived from the kinin group of proteins. It consists of nine amino acids and is known for its physiological and pharmacological activities. This peptide fragment is characterized by its ability to dilate blood vessels and is involved in various biological processes.

Uses

Used in Pharmaceutical Research:
H-ARG-PRO-PRO-GLY-PHE-SER-PRO-OH ACETATE SALT is used as a research tool for studying the specificity and kinetics of kininase(s). This helps in understanding the mechanisms of action and potential therapeutic applications of related compounds.
Used in Cardiovascular Applications:
In the pharmaceutical industry, H-ARG-PRO-PRO-GLY-PHE-SER-PRO-OH ACETATE SALT is used as a vasodilator for treating conditions related to blood vessel constriction. It promotes blood vessel dilation through the release of prostacyclin, nitric oxide, and Endothelium Derived Hyperpolarizing Factor, which can help in managing hypertension and other cardiovascular diseases.
Used in Research on Kinin Group Proteins:
H-ARG-PRO-PRO-GLY-PHE-SER-PRO-OH ACETATE SALT is used as a model compound in the study of kinin group proteins, which are involved in various physiological processes, including inflammation, pain, and blood pressure regulation. This helps researchers gain insights into the structure-function relationships and potential therapeutic applications of these proteins.

InChI:InChI=1/C35H52N10O9/c36-22(10-4-14-39-35(37)38)31(50)44-16-6-12-26(44)33(52)43-15-5-11-25(43)30(49)40-19-28(47)41-23(18-21-8-2-1-3-9-21)29(48)42-24(20-46)32(51)45-17-7-13-27(45)34(53)54/h1-3,8-9,22-27,46H,4-7,10-20,36H2,(H,40,49)(H,41,47)(H,42,48)(H,53,54)(H4,37,38,39)/t22-,23-,24-,25-,26-,27-/m0/s1