23865-30-7

Basic information

• Product Name: Urea, N,N''-(phenylmethylene)bis-
• CAS NO: 23865-30-7
• Molecular Formula: C9H12N4O2
• Molecular Weight: 208.22
• Mol File: 23865-30-7.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: Urea, N,N''-(phenylmethylene)bis-(CAS DataBase Reference)
• NIST Chemistry Reference: Urea, N,N''-(phenylmethylene)bis-(23865-30-7)
• EPA Substance Registry System: Urea, N,N''-(phenylmethylene)bis-(23865-30-7)

Safety Data

• Hazardous Substances Data: 23865-30-7(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 57-13-6 urea 
• 141-97-9 ethyl acetoacetate 
• 7647-01-0 hydrogenchloride 

Downstream Products

• 123237-03-6 ethyl 6-methyl-4-phenyl-3,4-dihydropyrimidin-2(1H)-one-5-carboxylate 
• 484-47-9 lophine 
• 5157-15-3 3a,6a-diphenylglycoluril 
• 20970-67-6 1-(5-acetyl-4-phenyl-2,6-dimethyl-1,4-dihydropyridin-3-yl)ethanone 
• 25652-50-0 5-acetyl-6-methyl-4-phenyl-3,4-dihydropyrimidin-2(1H)-one 
• 30805-30-2 1,2,3,4,5,6-hexahydro-2-phenyl-1,3,5-triazin-4,6-dione 
• 1466-67-7 1,3-dibenzylurea 
• 7664-41-7 ammonia 
• 108-80-5 isocyanuric acid 
• 1185842-97-0 C₁₄H₁₂N₂O₂ 
• 121400-84-8 1,4-bis(5-phenyl-2,4,6,8-tetraaza-3,7-dioxobicyclo<3.3.0>octan-1-yl)benzene 
• 121400-87-1 1-phenyl-5-<4-(2-phenyl-1,2-dioxoethyl)phenyl>-2,4,6,8-tetraazabicyclo<3.3.0>octane-3,7-dione 
• 53219-49-1 9-(phenyl)-3,3,6,6-tetramethyl-1,2,3,4,5,6,7,8-octahydroacridine-1,8-dione 
• 2769-21-3 3,3,6,6-tetramethyl-9-phenyl-3,4,6,7,9,10-hexahydro-2H,5H-acridine-1,8-dione 

Relevant articles and documents

Eco-efficiency and scalable synthesis of bisamides in deep eutectic solvent

Solvents define a major part of the environmental performance of processes in chemical industry and also impact on cost, safety and health issues. In order to minimize the environmental impact resulting from the use of volatile organic solvents in chemica

Highly Efficient Synthesis of Substituted 3,4-Dihydropyrimidin-2-(1H)-ones (DHPMs) Catalyzed by Hf(OTf)4: Mechanistic insights into reaction pathways under metal Lewis acid catalysis and solvent-free conditions

In our studies on the catalytic activity of Group IVB transition metal Lewis acids, Hf(OTf)4 was identified as a highly potent catalyst for”one-pot, three-component” Biginelli reaction. More importantly, it was found that solvent-free conditions, in contrast to solvent-based conditions, could dramatically promote the Hf(OTf)4-catalyzed formation of 3,4-dihydro-pyrimidin-2-(1H)-ones. To provide a mechanistic explanation, we closely examined the catalytic effects of Hf(OTf)4 on all three potential reaction pathways in both “sequential bimolecular condensations” and “one-pot, three-component” manners. The experimental results showed that the synergistic effects of solvent-free conditions and Hf(OTf)4 catalysis not only drastically accelerate Biginelli reaction by enhancing the imine route and activating the enamine route but also avoid the formation of Knoevenagel adduct, which may lead to an undesired byproduct. In addition, 1H-MMR tracing of the H-D exchange reaction of methyl acetoacetate in MeOH-d4 indicated that Hf(IV) cation may significantly accelerate ketone-enol tautomerization and activate the β-ketone moiety, thereby contributing to the overall reaction rate.

One pot preparations N,N′-alkylidene bisamide derivatives catalyzed by Nano-TiCL4.SiO2 with antimicrobial studies of some products

Nano-TiCl4.SiO2 has been introduced to be an extremely efficient catalyst for the preparation of N,N′-alkylidene bisamides from various aldehydes and amides under mild conditions. We synthesized this solid Lewis acid catalyst by the