23877-94-3 Usage
General Description
AKOS 92897 is a chemical compound that is a member of the sulfonamide class of drugs. It is commonly used as an antibacterial agent, and specifically as a diuretic and antihypertensive medication. AKOS 92897 works by inhibiting the activity of the enzyme carbonic anhydrase, which leads to decreased sodium and water reabsorption in the kidneys, ultimately resulting in increased excretion of urine and decreased blood pressure. AKOS 92897 is also utilized in the treatment of glaucoma and certain seizure disorders. Overall, it is an important pharmaceutical compound with diverse therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 23877-94-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,8,7 and 7 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 23877-94:
(7*2)+(6*3)+(5*8)+(4*7)+(3*7)+(2*9)+(1*4)=143
143 % 10 = 3
So 23877-94-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H8N2O2/c1-7-5-6-8-9(11-7)3-2-4-10(8)12(13)14/h2-6H,1H3
23877-94-3Relevant articles and documents
Approach to the synthesis of 8-nitroquinoline-2-carboxylic acid in high yield
Gadomsky, S. Ya.,Yakuschenko
, p. 816 - 818 (2016/12/27)
A synthesis of 8-nitroquinoline-2-carboxylic acid was optimized, using the following basic scheme of transformations: 1) nitration of 2-methylquinoline with subsequent separation of a mixture of isomeric 8-nitroand 5-nitro-2-methylquinolines; 2) oxidation of the methyl group in 2-methyl-8-nitroquinoline (including consecutive steps of bromination and hydrolysis in aqueous sulfuric acid). A new method for the separation of isomeric 8-nitroand 5-nitro-2methylquinolines was suggested. The optimal conditions for the final step of hydrolysis were selected, which gave almost quantitative yield of 8-nitroquinoline-2-carboxylic acid.
5-SUBSTITUTED QUINOLINE AND ISOQUINOLINE DERIVATIVES, A METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS ANTIPHLOGISTICS
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Page/Page column 28, (2008/06/13)
The invention relates to compounds of general formulas (IIa) or (IIb) and to their use as medicaments.
