23885-17-8

Basic information

• Product Name: 1,1,1,2-tetrafluoro-4-iodo-2-(trifluoromethyl)decane
• CAS NO: 23885-17-8
• Molecular Weight: 408.141
• Mol File: 23885-17-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,1,1,2-tetrafluoro-4-iodo-2-(trifluoromethyl)decane(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1,1,2-tetrafluoro-4-iodo-2-(trifluoromethyl)decane(23885-17-8)
• EPA Substance Registry System: 1,1,1,2-tetrafluoro-4-iodo-2-(trifluoromethyl)decane(23885-17-8)

Safety Data

• Hazardous Substances Data: 23885-17-8(Hazardous Substances Data)

Upstream product

• 111-66-0 oct-1-ene 
• 677-69-0 perfluoroisopropyl iodide 

Relevant articles and documents

Visible-Light-Mediated Iodoperfluoroalkylation of Alkenes in Flow and Its Application to the Synthesis of a Key Fulvestrant Intermediate

Two efficient continuous flow iodoperfluoroalkylation methods are described: using 0.05 mol % perylene diimide (PDI) photocatalyst under 450 nm irradiation or substoichiometric triethylamine under 405 nm irradiation. These methods enable dramatically elevated productivity versus batch processes. The triethylamine-mediated method is explored mechanistically and in substrate scope. The gram-scale synthesis of an active pharmaceutical ingredient side chain is also reported in flow, via a photochemical iodoperfluoroalkylation followed by hydrogenolysis.

A NEW TIN(II) CHLORIDE-SILVER(I) ACETATE OR -LEAD(II) BROMIDE REAGENT FOR THE ADDITION OF F-ALKYL IODIDES TO ALKENES

A tin(II) chloride-silver(I) acetate or tin(II) chloride-lead(II) bromide reagent can efficiently promote the addition of F-alkyl iodides to various alkenes in anhydrous methanol at room temperature to afford the corresponding F-alkylated iodides in fairl