23909-16-2Relevant articles and documents
Enantioselective Synthesis of N,S-Acetals by an Oxidative Pummerer-Type Transformation using Phase-Transfer Catalysis
Biswas, Souvagya,Kubota, Koji,Orlandi, Manuel,Turberg, Mathias,Miles, Dillon H.,Sigman, Matthew S.,Toste, F. Dean
supporting information, p. 589 - 593 (2018/02/21)
Reported is the first enantioselective oxidative Pummerer-type transformation using phase-transfer catalysis to deliver enantioenriched sulfur-bearing heterocycles. This reaction includes the direct oxidation of sulfides to a thionium intermediate, followed by an asymmetric intramolecular nucleophilic addition to form chiral cyclic N,S-acetals with moderate to high enantioselectivites. Deuterium-labelling experiments were performed to identify the stereodiscrimination step of this process. Further analysis of the reaction transition states, by means of multidimensional correlations and DFT calculations, highlight the existence of a set of weak noncovalent interactions between the catalyst and substrate that govern the enantioselectivity of the reaction.
Copper(I) complexes of N-centered aliphatic tripodal trithioether ligands - Adjustment of complex geometry by variation of spacer lengths
Blomenkemper, Marc,Schr?der, Henning,Pape, Tania,Hahn, F. Ekkehardt
experimental part, p. 76 - 80 (2011/03/22)
A series of novel aliphatic tripodal trithioether ligands 4-6 differing in the lengths of the alkyl chains between central nitrogen atom and sulfur donor function has been synthesized. The neutral ligands 4-6 react with copper(I) under formation of the mo
Dimethyl tyrosyl amide sulfides, sulfoxides and sulfones
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, (2008/06/13)
The present invention relates to new compounds of the formula STR1 and the pharmaceutically acceptable salts thereof and the enantiomers thereof, wherein R1 is H, lower alkyl, alkenyl, aralkyl, or C(O)R2 wherein R2 is lowe
