239095-84-2

Basic information

• Product Name: 2,3-dibromo-6,7-dichloro-1,2,3,4-tetrahydroquinoxaline
• Synonyms: 2,3-dibromo-6,7-dichloro-1,2,3,4-tetrahydroquinoxaline;2,3-dibroMo-6,7-dichloroquinoxaline
• CAS NO: 239095-84-2
• Molecular Formula: C₈H₂Br₂Cl₂N₂
• Molecular Weight: 360.863
• Mol File: 239095-84-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 404.6°C at 760 mmHg
• Flash Point: 198.5°C
• Appearance: /
• Density: 1.994g/cm³
• Vapor Pressure: 9.36E-07mmHg at 25°C
• Refractive Index: 1.648
• Storage Temp.: 2-8°C
• PKA: -7.52±0.48(Predicted)
• CAS DataBase Reference: 2,3-dibromo-6,7-dichloro-1,2,3,4-tetrahydroquinoxaline(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-dibromo-6,7-dichloro-1,2,3,4-tetrahydroquinoxaline(239095-84-2)
• EPA Substance Registry System: 2,3-dibromo-6,7-dichloro-1,2,3,4-tetrahydroquinoxaline(239095-84-2)

Safety Data

• Hazardous Substances Data: 239095-84-2(Hazardous Substances Data)

Usage

General Description

2,3-dibromo-6,7-dichloro-1,2,3,4-tetrahydroquinoxaline is a chemical compound with the molecular formula C8H6Br2Cl2N. It is a type of quinoxaline derivative and consists of two bromine atoms, two chlorine atoms, and a tetrahydroquinoxaline ring structure. 2,3-dibromo-6,7-dichloro-1,2,3,4-tetrahydroquinoxaline is used in organic synthesis and drug development due to its potential pharmacological properties. It has been studied for its potential use in pharmaceuticals, including as a central nervous system depressant and for its antimicrobial activity. Under specific conditions and in controlled environments, 2,3-dibromo-6,7-dichloro-1,2,3,4-tetrahydroquinoxaline shows promising potential for various applications in medicinal and pharmaceutical chemistry.

InChI:InChI=1/C8H6Br2Cl2N2/c9-7-8(10)14-6-2-4(12)3(11)1-5(6)13-7/h1-2,7-8,13-14H

Upstream product

• 25983-13-5 6,7-dichloro-1,4-dihydroquinoxaline-2,3-dione 
• 5348-42-5 4,5-Dichloro-1,2-phenylenediamine 

Downstream Products

• 239094-97-4 N1-(3-([2,2’-bithiophen]-5-yl)-6,7-dichloroquinoxalin-2-yl)-N4,N4-diethylbutane-1,4-diamine 
• 239094-83-8 N'-[3-(1-benzenesulfonyl-1H-indol-2-yl)-6,7-dichloro-quinoxalin-2-yl]-N,N-diethyl-butane-1,4-diamine 

Relevant articles and documents

Synthesis and structure-activity relationship of 2-amino-3-heteroaryl-quinoxalines as non-peptide, small-molecule antagonists for interleukin-8 receptor

Interleukin-8 modulation is implicated in many inflammatory and cancer diseases. Starting from a mass-screening hit, the synthesis and structure-activity relationship of 2-amino-3-heteroarylquinoxalines as non-peptide, small molecule interleukine-8 receptor antagonists have been developed. The optimized derivatives, PD 0210293 (13y) and PD 0220245 (13r), show inhibition of both IL-8 receptor binding and IL-8-mediated neutrophil chemotaxis.