239100-21-1Relevant articles and documents
Synthesis of putative metabolites of 1α,25-dihydroxy-2β-(3-hydroxypropoxy)vitamin D3 (ED-71)
Ono, Yoshiyuki,Watanabe, Hiroyoshi,Taira, Ikuo,Takahashi, Keisuke,Ishihara, Jun,Hatakeyama, Susumi,Kubodera, Noboru
, p. 529 - 540 (2007/10/03)
1α,25-Dihydroxy-2β-(3-hydroxypropoxy)vitamin D3 (ED-71), an analog of active vitamin D3, 1α,25-dihydroxyvitamin D3 [1,25(OH)2D3] is under phase III clinical trials in Japan for the treatment of osteop
Convergent synthesis of 1α-hydroxyvitamin D5
Gao, Ling-Jie,Zhao, Xu-Yang,Vandewalle, Maurits,De Clercq, Pierre
, p. 2755 - 2759 (2007/10/03)
An eleven-step, high-yielding (46%) synthesis of 1α-hydro-xyvitamin D5 (2) starting from Vitamin D2 (4) is described, in which a Julia olefination sequence is used for the construction of the (24R)-ethyl-substituted side chain.