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23918-98-1

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23918-98-1 Usage

Description

4-(9-ADENYL)-D-ERYTHRO-2,3-DIHYDROXYBUTYRIC ACID, also known as Eritadenine, is an alkaloid with the empirical formula C9H11N504. It is the D-Erythro-form of the base and appears as a pale yellow solid. Eritadenine has melting points recorded at 279°C (dec.) by Kamiya et al and 261-263°C (dec.) by Chibata and his colleagues. The alkaloid exhibits specific rotations of [α]D+ 16° (N-HCl) and [α]D + 50° (0.1 N-NaOH). Its ultraviolet spectrum in H2O has a single absorption maximum at 261.5 nm, which shifts to 259.5 nm in N-HCl and 262 nm in N-NaOH. Eritadenine can form a methyl ester with a melting point of 231°C (dec.) and a diacetate with a melting point of 225°C (dec.).

Uses

Used in Hypocholesterolemic Applications:
Eritadenine is used as a hypocholesterolemic agent, isolated from shiitake mushrooms, and affects phospholipid and linoleic acid metabolisms. It is a potent inhibitor of S-adenosyl-L-homocysteine hydrolase (SAHH), which helps in decreasing total cholesterol levels in plasma.

References

Chibata et al., Experientia, 25,1237 (1969)Kamiya et al., Tetrahedron Lett., 4729 (1969)

Check Digit Verification of cas no

The CAS Registry Mumber 23918-98-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,9,1 and 8 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 23918-98:
(7*2)+(6*3)+(5*9)+(4*1)+(3*8)+(2*9)+(1*8)=131
131 % 10 = 1
So 23918-98-1 is a valid CAS Registry Number.
InChI:InChI=1/C9H11N5O4/c10-7-5-8(12-2-11-7)14(3-13-5)1-4(15)6(16)9(17)18/h2-4,6,15-16H,1H2,(H,17,18)(H2,10,11,12)/t4-,6-/m1/s1

23918-98-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-(9-ADENYL)-D-ERYTHRO-2,3-DIHYDROXYBUTYRIC ACID

1.2 Other means of identification

Product number -
Other names Lentysine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:23918-98-1 SDS

23918-98-1Relevant articles and documents

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Kawasu et al.

, p. 1047 (1970)

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Kamiya et al.

, p. 899,902, 905 (1972)

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Synthesis and antiviral activity of stereoisomeric eritadenines

Holy,Votruba,De Clercq

, p. 1392 - 1407 (2007/10/02)

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