23950-58-5 Usage
Description
Propyzamide, also known as Pronamide, is a member of the benzamides class resulting from the formal condensation of the carboxy group of 3,5-dichlorobenzoic acid with the amino group of 2-methylbut-3-yn-2-amine. It is a white solid and is used as a selective herbicide.
Uses
Used in Agriculture:
Propyzamide is used as a pre-emergence or post-emergence herbicide for controlling a wide range of annual and perennial grasses and certain annual broadleaf weeds. It is primarily used on crops such as lettuce, alfalfa, blueberries, ornamentals, fruit trees, forage legumes, and on pastures and rangelands.
Used in Ornamental Trees and Shrubs:
Propyzamide is used as a selective herbicide to control many perennial and annual grasses and broad-leaved weeds in ornamental trees and shrubs.
Used in Forestry:
Propyzamide is used as a herbicide in forestry to control unwanted vegetation and promote the growth of desired tree species.
Used in Fruits and Vegetables:
Propyzamide is used as a herbicide in the cultivation of fruits and vegetables to control weeds and improve crop yield.
Chemical Properties:
Propyzamide is a white solid with colorless crystalline properties. It is available in wettable powder and granular formulations and is registered for use in the U.S. and EU countries. It is considered a U.S. EPA restricted Use Pesticide (RUP).
Reactivity Profile
3,5-DICHLORO-N-(1,1-DIMETHYL-2-PROPYNYL)BENZAMIDE is a chlorinated amide. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
Trade name
BENZAMIDE?; CAMPBELL'S RAPIER?; CLANEX?; KERB?; KERB 50 W?; KERB? PROPYZAMIDE 50; RH-315 RAPIER?; RONAMID?
Potential Exposure
A potential danger to those involved
in the manufacture, formulation and application of this
selective herbicide.
Environmental Fate
Biological. In the presence of suspended natural populations from unpolluted aquatic
systems, the second-order microbial transformation rate constant determined in the laboratory was reported to be 5 × 10–14 L/organisms-hour (Steen, 1991).
Soil. The major soil metabolite is 2-(3,5-dichlorophenyl)-4,4-dimethyl-5-methyleneoxazoline. The half-life in soil is approximately 30 days at 25°C (Hartley and Kidd, 1987).
Residual activity in soil is limited to approximately 2–6 months (Hartley and Kidd, 1987).
Chemical/Physical. Emits toxic fumes of nitrogen oxides and chlorine when heated
to decomposition (Sax and Lewis, 1987).
Propyzamide is hydrolyzed to 3,5-dichlorobenzoate by refluxing under strongly acidic
conditions (Humburg et al., 1989).
Shipping
UN3077 Environmentally hazardous substances,
solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous haz-
ardous material, Technical Name Required.
Incompatibilities
Incompatible with oxidizers (chlorates,
nitrates, peroxides, permanganates, perchlorates, chlorine,
bromine, fluorine, etc.); contact may cause fires or explo-
sions. Keep away from alkaline materials, strong bases,
strong acids, oxoacids, epoxides. Compounds of the car-
boxyl group react with all bases, both inorganic and
organic (i.e., amines) releasing substantial heat, water and a
salt that may be harmful. Incompatible with arsenic com-
pounds (releases hydrogen cyanide gas), diazo compounds,
dithiocarbamates, isocyanates, mercaptans, nitrides, and
sulfides (releasing heat, toxic and possibly flammable
gases), thiosulfates and dithionites (releasing hydrogen
sulfate and oxides of sulfur).
Waste Disposal
Consult with environmental
regulatory agencies for guidance on acceptable disposal
practices. Generators of waste containing this contaminant
(≥100 kg/mo) must conform with EPA regulations govern-
ing storage, transportation, treatment, and waste disposal.
In accordance with 40CFR165, follow recommendations
for the disposal of pesticides and pesticide containers. Must
be disposed properly by following package label directions
or by contacting your local or federal environmental control
agency, or by contacting your regional EPA office.
Check Digit Verification of cas no
The CAS Registry Mumber 23950-58-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,9,5 and 0 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 23950-58:
(7*2)+(6*3)+(5*9)+(4*5)+(3*0)+(2*5)+(1*8)=115
115 % 10 = 5
So 23950-58-5 is a valid CAS Registry Number.
InChI:InChI=1/C12H11Cl2NO/c1-4-12(2,3)15-11(16)8-5-9(13)7-10(14)6-8/h1,5-7H,2-3H3,(H,15,16)
23950-58-5Relevant articles and documents
Radical Carbonyl Propargylation by Dual Catalysis
Huang, Huan-Ming,Bellotti, Peter,Daniliuc, Constantin G.,Glorius, Frank
supporting information, p. 2464 - 2471 (2020/12/07)
Carbonyl propargylation has been established as a valuable tool in the realm of carbon–carbon bond forming reactions. The 1,3-enyne moiety has been recognized as an alternative pronucleophile in the above transformation through an ionic mechanism. Herein, we report for the first time, the radical carbonyl propargylation through dual chromium/photoredox catalysis. A library of valuable homopropargylic alcohols bearing all-carbon quaternary centers could be obtained by a catalytic radical three-component coupling of 1,3-enynes, aldehydes and suitable radical precursors (41 examples). This redox-neutral multi-component reaction occurs under very mild conditions and shows high functional group tolerance. Remarkably, bench-stable, non-toxic, and inexpensive CrCl3 could be employed as a chromium source. Preliminary mechanistic investigations suggest a radical-polar crossover mechanism, which offers a complementary and novel approach towards the preparation of valuable synthetic architectures from simple chemicals.
NURR1 RECEPTOR MODULATORS
-
Paragraph 0646; 1971-1973, (2020/09/08)
Described herein, inter alia, are Nurr1 receptor modulators and uses thereof. In an aspect is provided a method for treating a disease associated with dysregulation and/or degeneration of dopaminergic neurons in the central nervous system of a subject in need thereof, the method including administering to the subject in need thereof a therapeutically effective amount of a compound described herein.
A method for preparing alkyne benzoyl grass amine (by machine translation)
-
, (2018/04/01)
The present invention provides a method for preparing alkyne benzoyl grass amine, comprising a condensation step: by parts by mass to 3 - amino - 3 - methyl [...] 100 - 105 parts, triethylamine 2 - 5 parts and solvent 100 - 500 parts into 10% -32% ω of sodium hydroxide solution 200 - 400 parts by, after stir, dropping 3, 5 - dichloro benzoyl chloride 100 - 105 parts, temperature control in 12 - 15 °C, after dropping, thermal insulation 1 - 5 hours. The alkyne benzoyl grass amine preparation method of the advantage of high purity of the product. (by machine translation)
