23953-00-6

Basic information

• Product Name: (S)-(-)-2-METHOXYPROPIONIC ACID
• Synonyms: (S)-(-)-2-METHOXYPROPIONIC ACID;(S)-(+)-2-METHOXYPROPIONIC ACID;RARECHEM AL BO 1222;(S)-(-)-2-Methoxypropionic acid,98%;(2S)-2-Methoxy-propanoic Acid;(S)-2-Methoxypropanoic acid;propanoic acid, 2-methoxy-, (2s)-
• CAS NO: 23953-00-6
• Molecular Formula: C₄H₈O₃
• Molecular Weight: 104.1
• Product Categories: Chiral Reagents
• Mol File: 23953-00-6.mol
• Article Data: 8

Chemical Properties

• Melting Point: 124-125 °C
• Boiling Point: 99°C/20mmHg
• Flash Point: 87.1°C
• Appearance: Clear slightly yellow/Liquid
• Density: 1.1141 (rough estimate)
• Vapor Pressure: 0.144mmHg at 25°C
• Refractive Index: 1.4132-1.4152
• Storage Temp.: Refrigerator
• Solubility: Chloroform, Ethyl Acetate, Methanol
• PKA: 3.59±0.10(Predicted)
• CAS DataBase Reference: (S)-(-)-2-METHOXYPROPIONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(-)-2-METHOXYPROPIONIC ACID(23953-00-6)
• EPA Substance Registry System: (S)-(-)-2-METHOXYPROPIONIC ACID(23953-00-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38-41
• Safety Statements: 37/39-26-39
• Hazardous Substances Data: 23953-00-6(Hazardous Substances Data)

Usage

Description

(S)-(-)-2-METHOXYPROPIONIC ACID, with the CAS number 23953-00-6, is a liquid compound that is valuable in the field of organic synthesis. It is an essential building block for creating various chemical compounds and has a wide range of applications across different industries.

Uses

Used in Pharmaceutical Industry:
(S)-(-)-2-METHOXYPROPIONIC ACID is used as a synthetic intermediate for the development of pharmaceutical compounds. Its unique chemical properties allow it to be a key component in the synthesis of drugs with specific therapeutic effects.
Used in Chemical Industry:
(S)-(-)-2-METHOXYPROPIONIC ACID is used as a reagent in the chemical industry for various chemical reactions. Its liquid state facilitates easy handling and mixing with other chemicals, making it a versatile component in the production of different chemical products.
Used in Research and Development:
(S)-(-)-2-METHOXYPROPIONIC ACID is used as a research compound in the field of organic chemistry. It is essential for understanding the properties and behavior of similar compounds and for developing new synthetic methods and applications.
Used in Agricultural Industry:
(S)-(-)-2-METHOXYPROPIONIC ACID is used as a building block for the synthesis of agrochemicals, such as pesticides and herbicides. Its role in creating these compounds helps improve crop yield and protect plants from harmful pests and diseases.

InChI:InChI=1/C4H8O3/c1-3(7-2)4(5)6/h3H,1-2H3,(H,5,6)/t3-/m0/s1

Upstream product

• 41918-08-5 ethyl (S)-2-methoxypropanoate 
• 4324-37-2 2-methoxypropionic acid 
• 124-41-4 sodium methylate 
• 598-72-1 2-Bromopropionic acid 
• 139265-31-9 (S)-2-Methoxy-propionic acid 4-nitro-phenyl ester 
• 54656-65-4 (S)-2-methoxypropionic acid methyl ester 

Downstream Products

• 23943-98-8 (-)-(S)-2-methoxy-propionyl chloride 
• 139265-31-9 (S)-2-Methoxy-propionic acid 4-nitro-phenyl ester 
• 885060-21-9 C₂₆H₃₁F₂N₃O₄S 
• 1018690-25-9 3-(5-(2,5-difluorophenyl)-3-((S)-2-methoxypropanoyl)-2-phenyl-2,3-dihydro-1,3,4-thiadiazol-2-yl)propanenitrile 
• 1018690-28-2 C₂₅H₂₉F₂N₃O₅S 
• 1018690-33-9 C₂₆H₃₁F₂N₃O₅S 
• 1018783-78-2 C₃₀H₃₈F₂N₄O₆S 
• 1018690-42-0 [5-(2,5-difluoro-phenyl)-3-((S)-2-methoxy-propionyl)-2-phenyl-2,3-dihydro-[1,3,4]thiadiazol-2-ylmethoxy]-acetonitrile 
• 1185280-31-2 (S)-3-(5-(5-(1-methoxyethyl)-1,2,4-oxadiazol-3-ylamino)-2-methylphenyl)-1,7-dimethyl-1,6-naphthyridin-2(1H)-one 
• 1166400-13-0 tetrakis{4-[(2S)-methoxypropionate]phenyl}ethene 
• 1231924-05-2 (S)-2-methoxy-1-(4-(3-(4-(5-methylpyridin-2-ylamino)phenoxy)pyrazin-2-yl)piperidin-1-yl)propan-1-one 
• 1345848-26-1 (S)-N-{2,5-difluoro-4-[2-(2-methoxypropionylamino)pyridin-4-yloxy]phenyl}-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide 
• 1220626-85-6 (S)-N-(4-((4-(3-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)ureido)naphthalen-1-yloxy)methyl)pyridin-2-yl)-2-methoxypropanamide 
• 1612141-65-7 (S)-4-hexyl-2-(2-methyl-1,3-dioxan-2-yl)-phenyl 2-methoxypropanoate 

Relevant articles and documents

-

-

Hydrophilic Oligo(lactic acid)s Captured by a Hydrophobic Polyaromatic Cavity in Water

Biologically relevant hydrophilic molecules rarely interact with hydrophobic compounds and surfaces in water owing to effective hydration. Nevertheless, herein we report that the hydrophobic cavity of a polyaromatic capsule, formed through coordination-driven self-assembly, can encapsulate hydrophilic oligo(lactic acid)s in water with relatively high binding constants (up to Ka=3×105 m?1). X-ray crystallographic and ITC analyses revealed that the unusual host–guest behavior is caused by enthalpic stabilization through multiple CH–π and hydrogen-bonding interactions. The polyaromatic cavity stabilizes hydrolyzable cyclic di(lactic acid) and captures tetra(lactic acid) preferentially from a mixture of oligo(lactic acid)s even in water.

Syntheses of isotopically labelled L-?±-amino acids with an asymmetric centre at C-3

Approaches are described to the synthesis of a series of isotopically labelled L-a-amino acids each with an asymmetric centre at C-3, including isoleucine, allo-isoleucine, threonine and allo-threonine. The methods may be simply adapted for the selective incorporation of an isotopic label at each site of L-valine including the selective labelling of either diastereotopic methyl group with carbon-13 and/or deuterium and labelling of the amine with nitrogen-15. ? The Royal Society of Chemistry 2000.