2396-08-9

Basic information

• Product Name: N,N-dimethyl-3-(pentafluoroethyl)aniline
• Synonyms: N,N-dimethyl-3-(pentafluoroethyl)aniline
• CAS NO: 2396-08-9
• Molecular Weight: 239.188
• Mol File: 2396-08-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N,N-dimethyl-3-(pentafluoroethyl)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-dimethyl-3-(pentafluoroethyl)aniline(2396-08-9)
• EPA Substance Registry System: N,N-dimethyl-3-(pentafluoroethyl)aniline(2396-08-9)

Safety Data

• Hazardous Substances Data: 2396-08-9(Hazardous Substances Data)

Upstream product

• 512-56-1 trimethyl phosphite 
• 710-74-7 3-(perfluoroethyl)aniline 
• 309-11-5 (pentafluoroethyl)benzene 
• 656-84-8 1-nitro-3-(pentafluoroethyl)benzene 
• 124916-48-9 (N,N-dimethylaniline)tricarbonylchromium 
• 124898-13-1 trimethyl(pentafluoroethyl)silane 
• 16518-62-0 3-bromo-N,N-dimethylaniline 

Relevant articles and documents

Stoichiometric and Catalytic Aryl-Perfluoroalkyl Coupling at Tri-tert-butylphosphine Palladium(II) Complexes

This Communication describes studies of Ph-RF (RF = CF3 or CF2CF3) coupling at Pd complexes of general structure (PtBu3)PdII(Ph)(RF). The CF3 analogue participates in fast Ph-CF3 coupling (II complex. Furthermore, they show that this undesired pathway can be circumvented by changing from a CF3 to a CF2CF3 ligand. Ultimately, the insights gained from stoichiometric studies enabled the identification of Pd(PtBu3)2 as a catalyst for the Pd-catalyzed cross-coupling of aryl bromides with TMSCF2CF3 to afford pentafluoroethylated arenes.