23983-06-4 Usage
Description
(2E)-2-(4-chlorobenzylidene)[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-one is a complex chemical compound that features a benzimidazol-3(2H)-one ring system, a thiazole ring, and a 4-chlorobenzylidene group. As a thiazole derivative, it holds potential in pharmaceutical and medicinal chemistry due to its unique molecular structure, which may confer various biological activities. Further research is necessary to fully explore its potential applications in drug development and other fields.
Uses
Used in Pharmaceutical Industry:
(2E)-2-(4-chlorobenzylidene)[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-one is used as a chemical intermediate for the development of new pharmaceutical compounds. Its unique structure may contribute to the discovery of novel drugs with specific biological activities, making it a valuable asset in medicinal chemistry research.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, (2E)-2-(4-chlorobenzylidene)[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-one serves as a key component in the synthesis of potential therapeutic agents. Its presence in various chemical reactions can lead to the creation of new molecules with targeted biological effects, enhancing the scope of available treatments for different diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 23983-06-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,9,8 and 3 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 23983-06:
(7*2)+(6*3)+(5*9)+(4*8)+(3*3)+(2*0)+(1*6)=124
124 % 10 = 4
So 23983-06-4 is a valid CAS Registry Number.
23983-06-4Relevant articles and documents
Microwave-assisted synthesis and in-vitro anti-tumor activity of 1,3,4-triaryl-5-N-arylpyrazole-carboxamides
Abdel-Aziz, Hatem A.,El-Zahabi, Heba S.A.,Dawood, Kamal M.
experimental part, p. 2427 - 2432 (2010/06/15)
Regioselective 1,3-dipolar cycloaddition of nitrilimines with 5-arylidene-2-arylimino-4-thiazolidinones and with 2-(4-arylidene)thiazolo[3,2-a]benzimidazol-3(2H)-ones afforded the corresponding 1,3,4-triaryl-5-N-arylpyrazole-carboxamides and pyrazolylbenzimidazoles. All reactions were carried out under conventional thermal heating and/or microwave irradiation. Both the pyrazole-5-carboxamides and pyrazolylbenzimidazoles were examined for their in-vitro anti-tumor activities against two tumor cell lines, Hep-2 and colon CaCo-2. Most of the obtained compounds exhibited significant activity against CaCo-2 and Hep-2 cell lines.
Synthesis of New 2-Substituted Benzylidenethiazolobenzimidazol-3(2H)-ones and Their Biological Activity
Soni, Namita,Barthwal, J. P.,Gupta, T. K.,Bhalla, T. N.,Parmar, S. S.,Bhargava, K. P.
, p. 785 - 788 (2007/10/02)
2-Substituted benzylidenethiazolobenzimidazol-3(2H)-ones (I-XIV) have been synthesized and found to possess anticonvulsant activity (0-60percent).These compounds also inhibit rat brain monoamine oxidase (MAO) (33.70-98.30percent) and succinate dehydrogenase (SDH) (25.72-78.95percent) in vitro of concentrations 4E-4 M and 6E-4 M, respectively.Structure-activity relationship has been dicussed.
