23999-21-5

Basic information

• Product Name: N,N-diethyl-3-(4-nitrophenoxy)propan-1-amine
• Synonyms: N,N-diethyl-3-(4-nitrophenoxy)propan-1-amine
• CAS NO: 23999-21-5
• Molecular Weight: 252.313
• Mol File: 23999-21-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: N,N-diethyl-3-(4-nitrophenoxy)propan-1-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-diethyl-3-(4-nitrophenoxy)propan-1-amine(23999-21-5)
• EPA Substance Registry System: N,N-diethyl-3-(4-nitrophenoxy)propan-1-amine(23999-21-5)

Safety Data

• Hazardous Substances Data: 23999-21-5(Hazardous Substances Data)

Upstream product

• 13094-50-3 1-(3-bromopropoxy)-4-nitrobenzene 
• 109-89-7 diethylamine 
• 100-02-7 4-nitro-phenol 
• 104-77-8 3-diethylaminopropyl chloride 
• 4535-85-7 3-diethylaminopropylchloride hydrochloride 
• 824-78-2 4-nitrophenol sodium salt 
• 28341-54-0 4-(4-nitrophenoxy)butanoic acid 

Downstream Products

• 23043-08-5 4-(3-diethylamino-propoxy)-phenylamine 
• 1394355-10-2 C₂₅H₃₁N₃O₂S₂ 
• 1394355-11-3 C₂₇H₃₃N₃O₂S₂ 
• 1394355-13-5 C₂₁H₂₅N₃O₂S₂ 
• 1394355-16-8 C₂₅H₂₇N₃O₂S₂ 
• 1394355-18-0 C₂₇H₂₈N₂O₂S₂ 
• 1394355-19-1 C₃₁H₃₂N₂O₂S₂ 
• 1394355-20-4 C₂₂H₂₅N₃O₂S₂ 
• 1394355-21-5 C₃₀H₄₁N₃O₃S₂ 
• 1394355-24-8 C₂₄H₂₇N₃O₃S₂ 
• 1394355-27-1 C₂₉H₂₉ClN₂O₃S₂ 
• 1394355-29-3 C₃₀H₃₁N₃O₄S₂ 
• 1394355-30-6 C₃₀H₃₁N₃O₄S₂ 
• 1394355-33-9 C₂₈H₂₉N₃O₄S₂ 

Relevant articles and documents

Novel heteroarylcarboxamide derivative or pharmacutically acceptable salt thereof, process for the preparation thereof and pharmaceutical composition for prevention or treatment of RAGE receptor related diseases containing the same as an active ingredient

The present invention refers to novel heterocyclic biting Carbox probably the id derivative acceptable salt, and manufacturing method thereof including RAGE associated active acetylcholinesterase receptor or pharmaceutical composition for preventing or treating disease is directed to. Heterocycle by the present invention a derivative biting Carbox probably the id RAGE receptor antagonism in by, nerve cells with the beta loss oh with wheat id RAGE conjunction with receptor, inhibiting moving into brain, the resulting beta Amyloid plaque formed 21 is known to effectively inhibit generation.. Furthermore, memory a chemicals that are important in the acetylcholine for decomposing an aromatic thus inhibiting acetylcholine s reel sacrifice , RAGE disease associated active acetylcholinesterase receptor or Alzheimer's disease, cerebrovascular dementia, dementia due to damage bean curd, multi blockade dementia, Alzheimer's disease or the like dementia alcoholic or mixed dementia multi blockade and including dementia, pick (pick) bottle, a smartcrew [...] -Jakob (Creutzfeldt-jakob) bottle, that thyroid gland symptoms , bean curd a blade Parkinson (Parkinson) bottle, Huntington's disease (Huntington) which is useful in preventing or treating, can be used.

SUBSTITUTED NAPHTHYRIDINES AND USE THEREOF AS MEDICINES

The invention relates to new substituted naphthyridines of formula 1, as well as pharmacologically acceptable salts, diastereomers, enantiomers, racemates, hydrates or solvates thereof, wherein R1 denotes a group A selected from among —O—R3, —NR3R4, —CR3R4R5, -(ethyne)-R3, —S—R3, —SO—R3 and SO2—R3 or R1 denotes a group B selected from among C6-10-aryl,five- to ten-membered, mono- or bicyclic heteroaryl with 1-3 heteroatoms selected independently of one another from among N, O and S; while this heteroaryl is linked to the structure according to formula 1 via either a C atom or an N atom,three- to ten-membered, mono- or bicyclic, saturated or partially saturated heterocyclic group with 1-3 heteroatoms selected independently of one another from among N, O and S, while this heterocyclic group is linked to the structure according to formula 1 via either a C atom or an N atom, and 5- to 11-membered spiro group which may optionally contain 1, 2 or 3 heteroatoms selected independently of one another from among N, O and S, while this spiro group is linked to the structure according to formula 1 via either a C atom or an N atom, while this group B may optionally be substituted as described in claim 1 and wherein R2 is and R3, R4, R5, R6, R6′, R7, R8, R9, R10, V, n and m may have the meanings given in claim 1, as well as pharmaceutical compositions containing these compounds.

Relations between physical-chemical properties, chemical reactivity and local anesthetic effect in some procaine analogues. (Change of the carboxyl-group). 26

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