2403-01-2

Basic information

• Product Name: 3-NITROPYRIDINE1-OXIDE
• Synonyms: 3-NITROPYRIDINE1-OXIDE
• CAS NO: 2403-01-2
• Molecular Formula: C₅H₄N₂O₃
• Molecular Weight: 140.09686
• Mol File: 2403-01-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 397.2°Cat760mmHg
• Flash Point: 194°C
• Appearance: /
• Density: 1.43g/cm³
• Vapor Pressure: 3.7E-06mmHg at 25°C
• Refractive Index: 1.601
• CAS DataBase Reference: 3-NITROPYRIDINE1-OXIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-NITROPYRIDINE1-OXIDE(2403-01-2)
• EPA Substance Registry System: 3-NITROPYRIDINE1-OXIDE(2403-01-2)

Safety Data

• Hazardous Substances Data: 2403-01-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C5H4N2O3/c8-6-3-1-2-5(4-6)7(9)10/h1-4H

Upstream product

• 2530-26-9 3-nitropyridine 
• 5236-76-0 2-methyl-3-nitropyridine 1-oxide 

Downstream Products

• 4548-45-2 2-chloro-5-nitropyridine 
• 5470-18-8 2-Chloro-3-nitropyridine 
• 1127562-46-2 C₁₃H₁₂N₂O₃ 
• 1127562-44-0 C₁₃H₁₂N₂O₃ 
• 26820-59-7 N-(4-chlorophenyl)-5-nitropyridin-2-amine 
• 26820-72-4 N-(4-chlorophenyl)-3-nitro-2-pyridinamine 
• 2402-97-3 3-bromopyridine N-oxide 

Relevant articles and documents

Regioselective Three-Component Reaction of Pyridine N-Oxides, Acyl Chlorides, and Cyclic Ethers

A novel three-component reaction of pyridine N-oxides, acyl chlorides, and cyclic ethers is described. Treatment of an electron-deficient pyridine N-oxide with an acyl chloride in the presence of a cyclic ether at 25-50 °C leads to a substituted pyridine as a single regioisomer in up to 58% isolated yield. Isotopic-labeling experiments and substrate scope support the reaction proceeding through a carbene intermediate.

OXIDATIVE DEMETHYLATION OF SOME METHYLNITROPYRIDINE 1-OXIDES

3-Nitropyridine 1-oxide and 5-methyl-3-nitropyridine 1-oxide are produced readily by oxidative demethylation using SeO2 of 2-methyl- and 2,5-dimethyl-3-nitropyridine 1-oxides.