2403-61-4

Basic information

• Product Name: 4-CHLOROBENZALDEHYDE DIETHYL ACETAL
• Synonyms: 4-CHLOROBENZALDEHYDE DIETHYL ACETAL;1-CHLORO-4-(DIETHOXYMETHYL)BENZENE;Benzaldehyde, p-chloro-, diethyl acetal;Benzene, 1-chloro-4-(diethoxymethyl)-;Nsc296500;p-Chlorobenzaldehyde diethyl acetal
• CAS NO: 2403-61-4
• Molecular Formula: C₁₁H₁₅ClO₂
• Molecular Weight: 214.69
• Mol File: 2403-61-4.mol
• Article Data: 25

Chemical Properties

• Boiling Point: 129 °C / 15mmHg
• Flash Point: 67.5°C
• Appearance: /
• Density: 1.08
• Vapor Pressure: 0.0359mmHg at 25°C
• Refractive Index: 1.4920-1.4960
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 4-CHLOROBENZALDEHYDE DIETHYL ACETAL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CHLOROBENZALDEHYDE DIETHYL ACETAL(2403-61-4)
• EPA Substance Registry System: 4-CHLOROBENZALDEHYDE DIETHYL ACETAL(2403-61-4)

Safety Data

• Hazardous Substances Data: 2403-61-4(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Synthesis, p. 330, 1984 DOI: 10.1055/s-1984-30832Tetrahedron Letters, 23, p. 1537, 1982 DOI: 10.1016/S0040-4039(00)87152-X

InChI:InChI=1/C11H15ClO2/c1-3-13-11(14-4-2)9-5-7-10(12)8-6-9/h5-8,11H,3-4H2,1-2H3

Upstream product

• 33598-76-4 1-chloro-4-(ethoxymethyl)benzene 
• 104-88-1 4-chlorobenzaldehyde 
• 64-17-5 ethanol 
• 873376-62-6 triethoxyantimony 
• 122-51-0 orthoformic acid triethyl ester 
• 3510-48-3 4-chlorobenzaldehyde azine 
• 97-93-8 triethylaluminum 
• 67-56-1 methanol 

Downstream Products

• 39512-66-8 (4-chloro-benzylidene)-[1,2,4]oxadiazol-3-yl-amine 
• 92832-15-0 α,α-bis(2-hydroxy-6-isopropyl-tropon-3yl)-4-chlorotoluene 
• 104-88-1 4-chlorobenzaldehyde 
• 64-17-5 ethanol 
• 3157-65-1 N-(p-chlorobenzylidene)-p-toluenesulfonamide 
• 36382-28-2 1-Chloro-4-(1,3,3-triethoxy-propyl)-benzene 
• 92594-57-5 α-ethoxy-p-chlorobenzylphosphonic acid diethyl ester 
• 33210-79-6 1-Chloro-4-(chloro-ethoxy-methyl)-benzene 
• 10359-09-8 2-(4-chlorophenyl)-1,3-dithiane 
• 6302-92-7 1-(bis(ethylthio)methyl)-4-chlorobenzene 
• 1126-46-1 Methyl 4-chlorobenzoate 
• 7335-27-5 ethyl 4-chlorobenzoate 
• 69900-95-4 2-(p-toluenesulfonyl)-3-(p-chlorophenyl)oxaziridine 
• 878274-47-6 C₂₅H₂₃ClO 

Relevant articles and documents

Practical acetalization and transacetalization of carbonyl compounds catalyzed by recyclable PVP-I

A novel PVP-I catalyzed acetalizations/transacetalizations of carbonyl compounds has been developed processing with a mild and easy handling fashion. Different types of Acyclic and cyclic acetals were prepared from carbonyl compounds or their acetals successfully. Further applications of newly developed catalytic combination were testified. This protocol featured with simplicity of operation, mild reaction condition, short reaction time, recyclable of catalyst and broad substrates scope with excellent yields.

Bis(perfluorooctanesulfonyl)imide supported on fluorous silica gel: Application to protection of carbonyls

The immobilization of bis(perfluorooctanesulfonyl)imide (HNPf2) on fluorous silica gel (FSG) and its utilization in protection of carbonyls have been investigated. This system is reasonably general and can be applied to converting several carbonyls to the corresponding acetals and ketals in good to excellent yields. There is no need for the use of anhydrous solvents or inert atmosphere. Recycling studies have shown that the FSG-supported HNPf2 catalyst can be readily recovered and reused several times without significant loss of activity.

Cobalt(II) schiff base functionalized mesoporous silica as an efficient and recyclable chemoselective acetalization catalyst

Cobalt(II) Schiff base functionalized mesoporous silica was synthesized from covalent attachment via the introduction of Co(OAc)2 to salicylaldimine functionalized mesoporous silica. The catalyst proved to be chemoselective one for the acetalization of aldehydes to the corresponding acetals in alcohol. The immobilized catalyst can be easily recovered and reused for at least ten reaction cycles without significant loss of its catalytic activity.