24034-72-8

Basic information

• Product Name: (6α)-14,18-Epoxy-3-hydroxy-5-oxoophiobola-7,19-dien-25-al
• Synonyms: (6α)-14,18-Epoxy-3-hydroxy-5-oxoophiobola-7,19-dien-25-al;Epicochliobolin A
• CAS NO: 24034-72-8
• Molecular Formula: C₂₅H₃₆O₄
• Molecular Weight: 400.55094
• Mol File: 24034-72-8.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (6α)-14,18-Epoxy-3-hydroxy-5-oxoophiobola-7,19-dien-25-al(CAS DataBase Reference)
• NIST Chemistry Reference: (6α)-14,18-Epoxy-3-hydroxy-5-oxoophiobola-7,19-dien-25-al(24034-72-8)
• EPA Substance Registry System: (6α)-14,18-Epoxy-3-hydroxy-5-oxoophiobola-7,19-dien-25-al(24034-72-8)

Safety Data

• Hazardous Substances Data: 24034-72-8(Hazardous Substances Data)

Upstream product

• 890027-31-3 (-)-tert-butyl-[(2R,4S,5S,6R,7S)-7-methoxymethoxymethyl-4,7-dimethyl-6-vinyl-1-oxaspiro[4.4]non-2-ylmethoxy]diphenylsilane 
• 890027-63-1 2-[(2R,4S,5S,6R,7S)-2-{[(tert-butyldiphenylsilyl)oxy]methyl}-7-[(methoxymethoxy)methyl]-4,7-dimethyl-1-oxaspiro[4.4]nonan-6-yl]ethan-1-ol 
• 1344673-76-2 (2R,3S,4S)-2-bromo-3-(tert-butyldimethylsilyl)oxymethyl-4-tert-butyldiphenylsilyloxycyclopentanone 
• 1344673-90-0 (2S,3S,4S)-2-bromo-3-tert-butyldimethylsilyloxymethyl-4-tert-butyldiphenylsilyloxycyclopentanone 
• 1344673-77-3 2-[(2R,4S,5S,6R,7S)-7-[(R)-((1S,2S,3S)-2-tert-butyldimethylsilyloxymethyl-3-tert-butyldiphenylsilyloxy-5-oxocyclopentyl)(hydroxy)methyl]-2-tert-butyldiphenylsilyloxymethyl-4,7-dimethyl-1-oxaspiro[4.4]non-6-yl]ethyl 2,2-dimethylpropanoate 
• 1344673-86-4 (1S,2S)-2-hydroxymethylcyclopent-3-enol 
• 1344673-87-5 (1S,2S)-2-(tert-butyldimethylsilyl)oxymethylcyclopent-3-en-1-ol 
• 1344673-88-6 tert-butyl{[(1S,2S)-2-(tert-butyldimethylsilyl)oxymethylcyclopent-3-en-1-yl]oxy}diphenylsilane 
• 1344673-89-7 (1R,2R,3S,4S)-2-bromo-3-(tert-butyldimethylsilyl)oxymethyl-4-(tert-butyldiphenylsilyl)oxycyclopentanol 
• 1344673-74-0 2-[(2R,4S,5S,6R,7R)-7-[(E)-((2S,3S)-2-tert-butyldimethylsilyloxymethyl-3-tert-butyldiphenylsilyloxy-5-oxocyclopentylidene)methyl]-2-tert-butyldiphenylsilyloxymethyl-4,7-dimethyl-1-oxaspiro[4.4]non-6-yl]ethyl 2,2-dimethylpropanoate 
• 1344673-78-4 2-[(2R,4S,5S,6R,7R)-7-[((1S,2S,3S)-2-tert-butyldimethylsilyloxymethyl-3-tert-butyldiphenylsilyloxy-5-oxocyclopentyl)methyl]-2-tert-butyldiphenylsilyloxymethyl-4,7-dimethyl-1-oxaspiro[4.4]non-6-yl]ethyl 2,2-dimethylpropanoate 
• 1344673-92-2 (1R,2S,3S,4S)-3-tert-butyldimethylsilyloxymethyl-4-tert-butyldiphenylsilyloxy-2-{[(2R,4S,5S,6R,7R)-2-tert-butyldiphenylsilyloxymethyl-6-(2-hydroxyethyl)-4,7-dimethyl-1-oxaspiro[4.4]non-7-yl]methyl}-1-methylcyclopentanol 
• 1344673-93-3 [(2R,4S,5S,6R,7R)-7-[((1S,2R,4S,5S)-5-tert-butyldimethylsilyloxymethyl-4-tert-butyldiphenylsilyloxy-2-hydroxy-2-methylcyclopentyl)methyl]-2-tert-butyldiphenylsilyloxymethyl-4,7-dimethyl-1-oxaspiro[4.4]non-6-yl]acetaldehyde 
• 1344673-94-4 (1R,2S,3S,4S)-2-{[(2R,4S,5S,6R,7R)-6-allyl-2-tert-butyldiphenylsilyloxymethyl-4,7-dimethyl-1-oxaspiro[4.4]non-7-yl]methyl}-3-tert-butyldimethylsilyloxymethyl-4-tert-butyldiphenylsilyloxy-1-methylcyclopentanol 

Relevant articles and documents

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Convergent total synthesis of (+)-ophiobolin A

At long last: The enantioselective total synthesis of the title compound, which was isolated in 1958, proceeds by a convergent approach. The assembly of the C,D-ring fragment and the A-ring fragment of the core structure is achieved by employing a Reforma