240405-20-3 Usage
Description
2,3-DINOR-11BETA-PROSTAGLANDIN F2ALPHA, also known as 2,3-dinor-11β-PGF2α, is a metabolite of PGD2, a prostaglandin involved in various physiological processes. It is a biomarker used to indicate increased levels of PGD2 in the body, which is particularly relevant in the context of mast cell activation disease (MCAD) and asthma.
Uses
Used in Medical Diagnostics:
2,3-DINOR-11BETA-PROSTAGLANDIN F2ALPHA is used as a diagnostic marker for [application reason] to identify and monitor mast cell activation disease (MCAD). The increased urinary excretion of this metabolite in patients with MCAD helps in the detection and assessment of the disease's severity.
Used in Asthma Research and Diagnosis:
In the field of respiratory medicine, 2,3-DINOR-11BETA-PROSTAGLANDIN F2ALPHA is used as a biomarker for [application reason] to study and diagnose asthma. The elevated levels of this metabolite in the urine of asthma patients are positively correlated with impaired lung function, making it a valuable tool for understanding the disease's progression and evaluating treatment efficacy.
Used in Pharmaceutical Research:
2,3-DINOR-11BETA-PROSTAGLANDIN F2ALPHA is used as a research compound for [application reason] to investigate the role of prostaglandins in various physiological processes and diseases. This knowledge can contribute to the development of new therapeutic strategies and medications targeting prostaglandin-related conditions.
Used in Toxicology and Environmental Studies:
In the field of toxicology and environmental science, 2,3-DINOR-11BETA-PROSTAGLANDIN F2ALPHA is used as a biomarker for [application reason] to assess the impact of environmental factors on human health. The analysis of this metabolite in biological samples can provide insights into the effects of pollutants and other harmful substances on the body's prostaglandin balance.
Check Digit Verification of cas no
The CAS Registry Mumber 240405-20-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,4,0,4,0 and 5 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 240405-20:
(8*2)+(7*4)+(6*0)+(5*4)+(4*0)+(3*5)+(2*2)+(1*0)=83
83 % 10 = 3
So 240405-20-3 is a valid CAS Registry Number.
240405-20-3Relevant articles and documents
iPF2α-III metabolism. First total synthesis of 2,3-dinor iPF2α-III, a primary β-oxidation metabolite
Kim, Seongjin,Jung, Young-Ju,Lawson, John A,FitzGerald, Garret A,Rokach, Joshua
, p. 8277 - 8280 (2001)
The total synthesis of a primary iPF2α-III metabolite, namely dinor iPF2α-III 8, is described. The successful synthesis was finally accomplished by generating the carboxylic acid group at the end of the synthesis so as to avoid formation of an α,β-unsaturated carboxylic acid, which is prone to undergo side reactions.
