24044-07-3

Basic information

• Product Name: 2-(2-THIENYL)-1,3-THIAZOLE-4-CARBOXYLIC ACID
• Synonyms: IFLAB-BB F2124-0616;CHEMBRDG-BB 4003398;2-THIEN-2-YL-1,3-THIAZOLE-4-CARBOXYLIC ACID;2-(2-THIENYL)-1,3-THIAZOLE-4-CARBOXYLIC ACID;2-(Thiophen-2-yl)thiazole-4-carboxylicacid;2-(2-thienyl)-1,3-thiazole-4-carboxylic acid(SALTDATA: FREE);4-Carboxy-2-(thien-2-yl)-1,3-thiazole, 2-(4-Carboxy-1,3-thiazol-2-yl)thiophene;2-thiophen-2-yl-1,3-thiazole-4-carboxylic acid
• CAS NO: 24044-07-3
• Molecular Formula: C₈H₅NO₂S₂
• Molecular Weight: 211.26
• Mol File: 24044-07-3.mol
• Article Data: 5

Chemical Properties

• Melting Point: 157 °C
• Boiling Point: 441.5°Cat760mmHg
• Flash Point: 220.8°C
• Appearance: /
• Density: 1.515±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 1.43E-08mmHg at 25°C
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-(2-THIENYL)-1,3-THIAZOLE-4-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-THIENYL)-1,3-THIAZOLE-4-CARBOXYLIC ACID(24044-07-3)
• EPA Substance Registry System: 2-(2-THIENYL)-1,3-THIAZOLE-4-CARBOXYLIC ACID(24044-07-3)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-22
• Safety Statements: 26-36/37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 24044-07-3(Hazardous Substances Data)

Usage

General Description

2-(2-Thienyl)-1,3-thiazole-4-carboxylic acid is a heterocyclic compound containing a thienyl ring and a thiazole ring with a carboxylic acid group attached to the fourth carbon atom. It is used in pharmaceutical research as a potential drug candidate for the treatment of various diseases. The compound has been found to exhibit anti-inflammatory, antiviral, and antitumor activities in preliminary studies. Its unique structure and properties make it a promising target for further investigation and potential drug development.

InChI:InChI=1/C8H5NO2S2/c10-8(11)5-4-13-7(9-5)6-2-1-3-12-6/h1-4H,(H,10,11)/p-1

Upstream product

• 24043-97-8 ethyl 2-(thiophen-2-yl)thiazole-4-carboxylate 
• 24044-05-1 2-thiophen-2-yl-thiazole-4,5-dicarboxylic acid 
• 20300-02-1 thiophene-2-carbothioamide 
• 14037-19-5 2-thiophen-2-yl-thiazole-4,5-dicarboxylic acid diethyl ester 
• 24044-03-9 2-thiophen-2-yl-thiazole-4,5-dicarboxylic acid 4-ethyl ester 
• 5813-89-8 2-thiophenylcarboxamide 
• 98-03-3 thiophene-2-carbaldehyde 
• 52-90-4 L-Cysteine 

Downstream Products

• 306934-98-5 2-(2-thienyl)-4-thiazolecarboxylic acid chloride 
• 1029432-59-4 C₂₃H₂₆N₄O₃S₂ 
• 1147108-96-0 N-(2-carbamoylphenyl)-2-(2-thienyl)-1,3-thiazole-4-carboxamide 

Relevant articles and documents

Determination of superoxide anion radical by modified CdTe quantum dots

A novel fluorescence probe for determination of superoxide anion radical (O2[rad]?) was developed with CdTe quantum dots(QDs) modified by thiophene-2-formaldehyde shrinked L-cysteine Schiff base, which was characterized by Fourier transform infrared (FT-IR), thermal gravimetric analysis (TGA), ultraviolet-visible (UV–vis) and fluorescent spectrum. The particle size of CdTe QDs was 3.1 nm as confirmed by X-ray powder diffraction pattern (XRD) and Transmission Electron Microscope (TEM) in presence of β-cysteamine (CA). The fluorescent results showed that the fluorescence intensity of CdTe QDs was decreased with modified Schiff base at 305 nm, but enhanced at 610 nm with O2[rad]? and showed an apparent linear dependence in the concentration scope of 2.0 × 10?5–1.0 × 10?4 mol L?1 (r = 0.9934) with a detection limit of 1.8 × 10?6 mol L?1, which exhibited high selectivity and stability towards O2[rad]?.

THIAZOLE COMPOUNDS, METHODS FOR PREPARATION AND USE THEREOF

The present invention relates to thiazole compounds of formula I, the method for preparation and use thereof. More specifically, the present invention relates to novel derivatives of natural product largazole, the method for preparing them and their uses

Synthesis of intermediates of thiazolo(4,5-d)pyridazine. I. Thiazole-carboxylic acids and derivatives

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