24108-44-9

Basic information

• Product Name: 3,5,6-Triphenyl-1,2,4-triazine
• Synonyms: 3,5,6-Triphenyl-1,2,4-triazine
• CAS NO: 24108-44-9
• Molecular Formula: C₂₁H₁₅N₃
• Molecular Weight: 309.3639
• Mol File: 24108-44-9.mol
• Article Data: 11

Chemical Properties

• Melting Point: 145-146 °C(Solv: ligroine (8032-32-4))
• Boiling Point: 504°Cat760mmHg
• Flash Point: 225.2°C
• Appearance: /
• Density: 1.167g/cm³
• Vapor Pressure: 8.65E-10mmHg at 25°C
• Refractive Index: 1.63
• PKA: 0.54±0.63(Predicted)
• CAS DataBase Reference: 3,5,6-Triphenyl-1,2,4-triazine(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5,6-Triphenyl-1,2,4-triazine(24108-44-9)
• EPA Substance Registry System: 3,5,6-Triphenyl-1,2,4-triazine(24108-44-9)

Safety Data

• Hazardous Substances Data: 24108-44-9(Hazardous Substances Data)

Usage

General Description

3,5,6-Triphenyl-1,2,4-triazine is a chemical compound with the molecular formula C18H13N3. It is a triazine-based compound that is often used as a light stabilizer and UV absorber in plastics and polymers to enhance their durability and resistance to degradation caused by exposure to sunlight. 3,5,6-Triphenyl-1,2,4-triazine is also known for its applications in the synthesis of organic materials and as a building block for the design of various functional molecules. It has aromatic properties and is composed of three phenyl rings attached to a central triazine ring, giving it a stable and rigid structure. Additionally, it has been studied for its potential pharmaceutical and biological activities, particularly as an anti-cancer agent and as a fluorescence probe in biological imaging.

InChI:InChI=1/C21H15N3/c1-4-10-16(11-5-1)19-20(17-12-6-2-7-13-17)23-24-21(22-19)18-14-8-3-9-15-18/h1-15H

Upstream product

• 36289-76-6 benzil bis(benzoylhydrazone) 
• 613-94-5 benzoic acid hydrazide 
• 134-81-6 benzil 
• 6830-78-0 3,6-diphenyl-1,2,4,5-tetrazine 
• 618-39-3 benzamidin 
• 34177-11-2 3-chloro-5,6-diphenyl-1,2,4-triazine 
• 133406-37-8 3,5,6-triphenyl-2,5-dihydro-1,2,4-triazin-4-ium chloride 
• 116178-05-3 3,6-diphenyl-1,2,4-triazine-5-carbonitrile 
• 73720-51-1 3-Phenyl-6-pyridin-2-yl-[1,2,4,5]tetrazine 
• 55824-85-6 1,3-Diphenyl-1-benzoyloxy-3-oxo-2-aza-1-propen 
• 55-21-0 benzamide 
• 108-86-1 bromobenzene 
• 28819-30-9 benzamidrazone 
• 501-65-5 diphenyl acetylene 

Downstream Products

• 484-47-9 lophine 
• 102469-79-4 3,5,6-triphenyl-1,2-dihydro-[1,2,4]triazine 
• 745-28-8 3,5,6-triphenyl-[1,2,4]triazine 1-oxide 
• 745-45-9 3,5,6-triphenyl-[1,2,4]triazine 2-oxide 
• 151724-24-2 1,3,4-Triphenyl-6,7-dihydro-5H-[2]pyrindine 
• 18076-30-7 3,4,5-triphenylpyrazole 
• 37469-28-6 3,5,6-triphenyl-2⁽⁴⁾,5-dihydro-1,2,4-triazine 
• 6931-31-3 2-phenyl-9,10-phenanthroimidazole 
• 222720-56-1 4-acetylamino-3,4,5-triphenyl-4H-pyrazole 
• 222720-55-0 1,4-diacetyl-3,5,6-triphenyl-1,4-dihydro-1,2,4-triazine 
• 151724-62-8 1,3,4-Triphenyl-6,7-dihydro-5H-[2]pyrindin-5-ol 
• 151724-39-9 1,3,4-Triphenyl-6,7-dihydro-5H-[2]pyrindine 2-oxide 
• 151724-51-5 Acetic acid 1,3,4-triphenyl-6,7-dihydro-5H-[2]pyrindin-5-yl ester 
• 33314-38-4 1-methyl-3,4,5-triphenyl-1H-pyrazole 

Relevant articles and documents

Gold-Catalyzed Oxidation of Internal Alkynes into Benzils and its Application for One-Pot Synthesis of Five-, Six-, and Seven-Membered Azaheterocycles

Internal alkynes have been shown to undergo oxidation to substituted benzils (1,2-diarylethane-1,2-diones) by α-picoline N-oxide in the presence of Ph3PAuNТf2 (5 mol-%). In addition to the unsubstituted benzil, the method allows preparing, under markedly mild conditions (50 °C in chlorobenzene), various non-symmetrical products, including heteroaromatic versions thereof which are much more difficult to obtain otherwise. This gold(I)-catalyzed transformation was integrated into one-pot reaction sequence delivering a range of 5- to 7-membered ring systems (imidazoles, quinoxalines, 1,2,4-triazines, pyrazines, and 1,4-diazepines), thus linking these important heterocyclic motifs to the internal alkyne reagent space.

Synthesis of 1,2,4-triazine derivatives via [4 + 2] domino annulation reactions in one pot

Simple and efficient [4 + 2] domino annulation reactions have been developed for the synthesis of 1,2,4-triazine derivatives. The strategies exhibit high performance with moderate to high yields, using easily available materials including ketones, aldehyd

Synthesis of trisubstituted 1,2,4-triazines in presence of NaHSO 4/SiO2

An efficient method for the synthesis of trisubstituted 1,2,4-triazines, phenanthro-1,2,4-triazines and acenaphtho-1,2,4-triazines derivatives by three-component condensation of benzil or phenanthrene-9,10-dione or acenaphthylene-1,2-dione, with acid hydr