24115-90-0Relevant articles and documents
Novel strategy to boost oral anticoagulant activity of blood coagulation enzyme inhibitors based on biotransformation into hydrophilic conjugates
Ishihara, Tsukasa,Koga, Yuji,Mori, Kenichi,Sugasawa, Keizo,Iwatsuki, Yoshiyuki,Hirayama, Fukushi
, p. 6324 - 6332 (2014)
The blood coagulation cascade represents an attractive target for antithrombotic drug development, and recent studies have attempted to identify oral anticoagulants with inhibitory activity for enzymes in this cascade, with particular attention focused on
Heterocyclic amido derivatives of substituted benzoic acids and therapeutic compositions which contain them as active principle
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, (2008/06/13)
Heterocyclic amido derivatives of substituted benzoic acids of general formula (I): in which:, R1 is H; 3-OCH3; 3-Cl; 4-Cl; 5-Cl; 3-CH3; 5-CH3; or 3-OH; -CH2-COOH; or -CH2-CO2-C