24123-91-9 Usage
Description
(2Z)-2-(naphthalen-1-ylmethylidene)-1-azabicyclo[2.2.2]octan-3-one, also known as N-methyl-2-naphthylidene-2-azabicyclo[2.2.2]octan-3-one, is a bicyclic lactam with a molecular formula of C18H17NO. It features a naphthalene ring and a bicyclo[2.2.2]octane ring, making it a unique chemical compound with interesting pharmacological properties. Its structure and functional groups contribute to its significance as a building block in organic chemistry and drug discovery.
Uses
Used in Pharmaceutical Industry:
(2Z)-2-(naphthalen-1-ylmethylidene)-1-azabicyclo[2.2.2]octan-3-one is used as a chemical intermediate for the synthesis of various pharmaceuticals and organic compounds. Its unique structure and functional groups make it a valuable component in the development of new drugs and therapeutic agents.
Used in Organic Chemistry:
(2Z)-2-(naphthalen-1-ylmethylidene)-1-azabicyclo[2.2.2]octan-3-one is used as a building block in organic chemistry, allowing for the creation of complex molecules and compounds. Its versatility and potential for modification make it an important tool in the field of chemical research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 24123-91-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,1,2 and 3 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 24123-91:
(7*2)+(6*4)+(5*1)+(4*2)+(3*3)+(2*9)+(1*1)=79
79 % 10 = 9
So 24123-91-9 is a valid CAS Registry Number.
24123-91-9Relevant articles and documents
Ruthenium-Catalyzed Highly Enantioselective Synthesis of cis-3-Quinuclidinols via DKR Asymmetric Transfer Hydrogenation
Luo, Zhonghua,Wang, Zhongqing,Sun, Guodong,Jian, Weilin,Jiang, Fengkai,Luan, Baolei,Li, Ridong,Zhang, Lei
supporting information, p. 4322 - 4326 (2020/06/04)
A method for the enantioselective synthesis of cis-3-quinuclidinols by Ru-catalyzed asymmetric transfer hydrogenation via dynamic kinetic resolution is described. The reaction proceeded under mild conditions using ammonium formate as the hydrogen donor, affording the products in high yields (up to 99%) with excellent diastereoselectivity (up to 99:1 dr) and enantioselectivity (95-99% ee). This protocol was applicable to gram-scale preparation with perfect enantioselectivity through simple recrystallization.
SYNTHESIS, STRUCTURE, AND PROPERTIES OF PYRAZOLOQUINUCLIDINE DERIVATIVES
Turchin, K. F.,Yanina, A. D.,Filipenko, T. Ya.,Mikhlina, E. E.,Sheinker, Yu. N.,Yakhtonov, L. N.
, p. 1039 - 1048 (2007/10/02)
It was shown by means of 1H and 13C NMR spectroscopy that the reaction of 2-arylmethylene-3-oxoquinuclidines with hydrazine hydrate gives 4a-hydroxy-7-aryl-4a,5,7,7a-tetrahydropyrazoloquinuclidines, which are stable in the crystalline state but undergo dehydration to the corresponding 7-aryl-6H-7,7a-dihydropyrazoloquinuclidines in solutions.The latter undergo cleavage to the 3-(4-piperidyl)-5-arylpyrazoles when they are heated in an alkaline medium.
