24164-13-4 Usage
General Description
Epitulipinolide is a natural product isolated from the marine sponge Epitrix ciconiae. It has been identified as a potent inhibitor of the protein kinase Cepsilon (PKCepsilon), which plays a role in various cellular processes including cell growth, proliferation, and apoptosis. Epitulipinolide has shown promising antiproliferative activity against several cancer cell lines, with potential for use in cancer therapy. Additionally, it has also exhibited anti-inflammatory and analgesic properties, making it a promising candidate for the development of new pharmaceutical compounds. Further research into the potential therapeutic applications of epitulipinolide is ongoing.
Check Digit Verification of cas no
The CAS Registry Mumber 24164-13-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,1,6 and 4 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 24164-13:
(7*2)+(6*4)+(5*1)+(4*6)+(3*4)+(2*1)+(1*3)=84
84 % 10 = 4
So 24164-13-4 is a valid CAS Registry Number.
InChI:InChI=1/C17H22O4/c1-10-6-5-7-11(2)9-15-16(12(3)17(19)21-15)14(8-10)20-13(4)18/h6,9,14-16H,3,5,7-8H2,1-2,4H3/b10-6+,11-9+/t14-,15-,16-/m1/s1
24164-13-4Relevant articles and documents
-
Watanabe,K.,Ohno,N.
, p. 709 (1982)
-
Acid Cyclization and Other Products of the Germacranolide Epoxide Lipiferolide
Wilton, John H.,Doskotch, Raymond W.
, p. 4251 - 4256 (2007/10/02)
A comparison was made of the products generated from lipiferolide (2) upon treatment with SOCl2, HCl, and BF3*Et2O.SOCl2 formed three epoxide-opened compounds, chlorhydrin 3 and two allylic alcohols, 4 and 5, three cyclization products of the guaianolide type, chloro compound 9 and olefins 1 and 10, as well as three novel bicyclodecanes, 6, 7, and 8.HCl generated the epoxide-opened substances 3, 4, and 5 and guaianolides 1, 9, and 10, but no cyclobutane products.BF3*Et2O gave fluorohydrin 11 as the major component and ketone 12, xanthanolide 13, and epitulipinolide (4,5-deoxylipiferolide) as compounds not observed from the other reagents, along with small yields of allylic alcohol 4 and guaianolides 1 and 10.
