24172-97-2Relevant articles and documents
Structure-based drug design of novel carborane-containing nicotinamide phosphoribosyltransferase inhibitors
Asawa, Yasunobu,Katsuragi, Kiyotaka,Sato, Akira,Yoshimori, Atsushi,Tanuma, Sei-ichi,Nakamura, Hiroyuki
, p. 2832 - 2844 (2019)
A series of carborane-containing NAMPT inhibitors were designed and synthesized based on the structure of compounds 1 and the NAMPT inhibitory activity was evaluated using NAMPT Colorimetric Assay. Among the compounds synthesized, compounds 2b and 2c show