2418-69-1

Basic information

• Product Name: H-ARG-PRO-OH SULFATE SALT
• Synonyms: H-ARG-PRO-OH SULFATE;H-ARG-PRO-OH SULFATE SALT;H-Arg-Pro-OH;arginylproline;(2S)-1-[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carboxylic acid;(2S)-1-[(2S)-2-amino-5-guanidino-pentanoyl]proline;(2S)-1-[(2S)-2-azanyl-5-[bis(azanyl)methylideneamino]pentanoyl]pyrrolidine-2-carboxylic acid
• CAS NO: 2418-69-1
• Molecular Formula: C₁₁H₂₁N₅O₃
• Molecular Weight: 369.39
• Mol File: 2418-69-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 576.6°Cat760mmHg
• Flash Point: 302.5°C
• Appearance: /
• Density: 1.51g/cm³
• Vapor Pressure: 8.48E-15mmHg at 25°C
• Refractive Index: 1.659
• Storage Temp.: -15°C
• PKA: 3.16±0.20(Predicted)
• CAS DataBase Reference: H-ARG-PRO-OH SULFATE SALT(CAS DataBase Reference)
• NIST Chemistry Reference: H-ARG-PRO-OH SULFATE SALT(2418-69-1)
• EPA Substance Registry System: H-ARG-PRO-OH SULFATE SALT(2418-69-1)

Safety Data

• Hazardous Substances Data: 2418-69-1(Hazardous Substances Data)

Usage

Description

H-ARG-PRO-OH SULFATE SALT is a sulfated salt form of H-arginyl-L-proline, an amino acid dipeptide with potential antifibrotic and anti-angiogenic activities. It is used in various biochemical and pharmacological research applications.
Used in Pharmaceutical Industry:
H-ARG-PRO-OH SULFATE SALT is used as a therapeutic agent for its potential antifibrotic and anti-angiogenic properties. It is being studied for its potential therapeutic applications in diseases such as pulmonary fibrosis, liver fibrosis, and certain types of cancers.
Used in Biochemical Research:
H-ARG-PRO-OH SULFATE SALT is used as a research compound to study its potential inhibitory effects on prolyl 4-hydroxylase, an enzyme involved in collagen synthesis, and its ability to disrupt signaling pathways involved in angiogenesis.
Further research is needed to fully understand the mechanisms and potential benefits of H-ARG-PRO-OH SULFATE SALT in clinical settings.

InChI:InChI=1/C11H21N5O3/c12-7(3-1-5-15-11(13)14)9(17)16-6-2-4-8(16)10(18)19/h7-8H,1-6,12H2,(H,18,19)(H4,13,14,15)

Upstream product

• 60189-46-0 Arg-Pro-pNA 

Relevant articles and documents

Catalytic properties of X-prolyl dipeptidyl aminopeptidase from Lactococcus lactis subsp. cremoris nTR.

An X-prolyl dipeptidyl aminopeptidase (X-PDAP; EC 3.4.14.5) was identified to be loosely bound on the inner cell membrane fraction of Lactococcus lactis subsp. cremoris nTR. The biosynthesis of X-PDAP was continuously increased before the late-log growth phase of the bacteria. Both Gly-Pro-pNA and Ala-Ala-pNA were hydrolyzed by X-PDAP; the kcat/Km value of the former was about 10-fold that of the latter. The Ki of X-Pro and Pro-X were more specific to X-PDAP than those of X-Ala. The enzyme splitting a dipeptide sequentially from beta-casomorphin as a model catalytic pattern was identified and some properties of the enzyme were further characterized.