241813-23-0

Basic information

• Product Name: N-tert-butyl-1-(2-(phenylethynyl)phenyl)methylenamine
• Synonyms: N-tert-butyl-1-(2-(phenylethynyl)phenyl)methylenamine
• CAS NO: 241813-23-0
• Molecular Weight: 261.367
• Mol File: 241813-23-0.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: N-tert-butyl-1-(2-(phenylethynyl)phenyl)methylenamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-tert-butyl-1-(2-(phenylethynyl)phenyl)methylenamine(241813-23-0)
• EPA Substance Registry System: N-tert-butyl-1-(2-(phenylethynyl)phenyl)methylenamine(241813-23-0)

Safety Data

• Hazardous Substances Data: 241813-23-0(Hazardous Substances Data)

Upstream product

• 6630-33-7 ortho-bromobenzaldehyde 
• 536-74-3 phenylacetylene 
• 59046-72-9 o-(phenylethynyl)benzaldehyde 
• 75-64-9 tert-butylamine 

Downstream Products

• 312612-62-7 4-iodo-3-phenylisoquinoline 
• 1404078-11-0 4-fluoro-3-phenylisoquinoline 
• 1312679-09-6 3-phenyl-4-(phenylsulfenyl)isoquinoline 
• 1402909-04-9 4-(butyltelluro)-3-phenylisoquinoline 
• 1402909-03-8 3-phenyl-4-(phenyltelluro)isoquinoline 
• 1402909-02-7 4-(buthylselenyl)-3-phenylisoquinoline 
• 1402909-01-6 3-phenyl-4-(2-tolylselenyl)isoquinoline 
• 1402909-00-5 4-(4-methoxyphenylselenyl)-3-phenylisoquinoline 
• 1402908-99-9 3-phenyl-4-[3-(trifluoromethyl)phenylselenyl]isoquinoline 
• 1402908-98-8 4-(4-chlorophenylselenyl)-3-phenylisoquinoline 
• 1402908-97-7 4-(4-fluorophenylselenyl)-3-phenylisoquinoline 
• 1402908-96-6 4-(4-methylphenylseleno)-3-phenylisoquinoline 
• 320371-79-7 4-(4-methoxybenzoyl)-3-phenylisoquinoline 

Relevant articles and documents

Cs2CO3 Catalyzed Intramolecular Aminocarbonylation of Alkynes: Synthesis of 3-Amino-1H-inden-1-ones from N-tert-Butyl-2-(1-alkynyl)benzaldimines

Synthesis of a wide variety of 3-amino-1H-inden-1-ones from N-tert-butyl-2-(1-alkynyl)benzaldimines via intramolecular aminocarbonylation of alkynes using Cs2CO3 as catalyst and air as oxidant has been developed. This highly atom-efficient, transition-metal-free reaction proceeds under thermal conditions. We propose that the reaction proceeds through an unprecedented 5-exo-dig cyclization of N-tert-butyl-2-(1-alkynyl)benzaldimines and thermal rearrangement of 3-methylene-2λ2-isoindolin-1-ols. (Figure presented.).

Hypervalent iodine compound containing heterocyclic ring as well as preparation method and application thereof

The invention discloses a hypervalent iodine compound containing a heterocyclic ring as well as a preparation method and application thereof. A structure of the compound is shown as a formula (I): theformula (I) is shown in the description, wherein R is selected from hydrogen, halogen, alkyl, alkoxy, halogenated alkyl, halogenated alkoxy, nitryl, cyano, hydroxyl or -COOR'; R' is alkyl or halogenated alkyl; and Het is substituted or non-substituted 1,4-benzopyranone, substituted or non-substituted quinolone, substituted or non-substituted isoquinoline, substituted or non-substituted thiobenzopyranone, substituted or non-substituted coumarin and substituted or non-substituted oxepin. The compound disclosed by the invention is novel in structure and is the hypervalent iodine compound containing the heterocyclic ring; the hypervalent iodine compound is stable in structure and simple in preparation method; and meanwhile, the hypervalent iodine compound has a very good inhibition effect onML-1 and MOLM-13 cells and has an extremely great application prospect on prevention and/or treatment effect on leukemia.

Synthesis of substituted isoquinolines via iminoalkyne cyclization using Ag(i) exchanged K10-montmorillonite clay as a reusable catalyst

Monosubstituted isoquinolines are synthesized in good to excellent yields by the Ag(i)-exchanged K10-montmorillonite clay catalyzed ring closure of iminoalkynes. This silver catalyzed ring closure is highly effective in cyclizing aryl- and alkyl-substituted iminoalkynes at 100 °C and accommodates a variety of iminoalkynes, thus affording a convenient route to the synthesis of isoquinolines. The other salient features of this procedure are its reusability, environmentally benign nature, high yield, operational simplicity with fewer steps, easy separation, and minimization of metallic wastes. The reaction proceeds smoothly in moderate yields and tolerates various functional groups. The solid catalyst can be readily recovered and reused. Notably, no additional base or other co-catalysts are needed. A plausible mechanism is proposed in which isoquinolines are formed via simultaneous bifunctional acid-base catalysis by Ag(i) clay. the Partner Organisations 2014.