24223-45-8

Basic information

• Product Name: (3,4-dihydroquinolin-1(2H)-yl)(2-hydroxyphenyl)methanone
• Synonyms: (3,4-dihydroquinolin-1(2H)-yl)(2-hydroxyphenyl)methanone
• CAS NO: 24223-45-8
• Molecular Weight: 253.301
• Mol File: 24223-45-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (3,4-dihydroquinolin-1(2H)-yl)(2-hydroxyphenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (3,4-dihydroquinolin-1(2H)-yl)(2-hydroxyphenyl)methanone(24223-45-8)
• EPA Substance Registry System: (3,4-dihydroquinolin-1(2H)-yl)(2-hydroxyphenyl)methanone(24223-45-8)

Safety Data

• Hazardous Substances Data: 24223-45-8(Hazardous Substances Data)

Upstream product

• 635-46-1 1,2,3,4-tetrahydroisoquinoline 
• 444-30-4 2-(trifluoromethyl)phenol 
• 1441-87-8 salicyloyl chloride 
• 69-72-7 salicylic acid 
• 118-55-8 phenyl Salicylate 

Relevant articles and documents

Intramolecular metal-free oxidative aryl-aryl coupling: An unusual hypervalent-iodine-mediated rearrangement of 2-substituted n-phenylbenzamides

Hypervalent-iodine-mediated oxidative coupling of the two aryl groups in either 2-acylamino-N-phenyl-benzamides or 2-hydroxy-N-phenylbenzamides, with concomitant insertion of the ortho-substituted N or O atom into the tether, has been described for the first time. This unusual metal-free rearrangement reaction involves an oxidative C(sp2)?C(sp2) aryl-aryl bond formation, cleavage of a C(sp2)?C(O) bond, and a lactamization/lactonization. Furthermore, unsymmetrical diaryl compounds can be easily obtained by removing the tether within the cyclized product.