24292-60-2 Usage
Description
Triphosphopyridine nucleotide disodium salt, also known as Nicotinamide adenine dinucleotide phosphate (NADP), is a coenzyme that is widely distributed in living matter. It participates in oxidation-reduction reactions and serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). NADP is a substance in which nicotinic acid amide adenine dinucleotide and a phosphate molecule are bound by an ester bond. It is a hydrogen receptor and can be used for the development and development of a variety of in vitro diagnostic reagents. It is a yellowish powder in appearance.
Uses
Used in Enzyme Catalysis:
Triphosphopyridine nucleotide disodium salt is used as a coenzyme in the method for preparing 2,4-Diamino Butyric Acid by enzyme catalysis.
Used in Redox Reactions:
Triphosphopyridine nucleotide disodium salt is used as a coenzyme in redox reactions, particularly in anaerobic reactions such as lipid and nucleic acid synthesis. It forms a redox pair with NADPH, and the NADPH/NADP ratio regulates the intracellular redox potential, thereby influencing metabolic reactions in vivo.
Used in Cytochrome P450 Systems:
Triphosphopyridine nucleotide disodium salt is used as a coenzyme couple in various cytochrome P450 systems and oxidase/reductase reaction systems, such as the thioredoxin reductase/thioredoxin system.
Used in Biotechnological Applications:
Triphosphopyridine nucleotide disodium salt is used for the quantification of glucose in glycogen and has also been used for the hexokinase assay.
Used in Pharmaceutical Development:
Triphosphopyridine nucleotide disodium salt is used as a hydrogen receptor for the development and development of a variety of in vitro diagnostic reagents.
Mechanism of action
β-Nicotinamide adenine dinucleotide NAD and β-nicotinamide adenine dinucleotide phosphate NADP are coenzymes necessary for cellular energy metabolism and play a central role in energy metabolism. In addition, purine nucleotides also play an important transfer role in biological processes. Protons in energy reactions are usually first transferred to NAD and NADP, then reduced to NADH and NADPH, and transferred to oxygen through electrons to release energy. The generated reduced NADH and NADPH are coenzymes of glutathione reductase and have important antioxidant functions.
Precautions
Protect from light and moisture. Keep cool and dry. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Store under inert gas.
Check Digit Verification of cas no
The CAS Registry Mumber 24292-60-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,2,9 and 2 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 24292-60:
(7*2)+(6*4)+(5*2)+(4*9)+(3*2)+(2*6)+(1*0)=102
102 % 10 = 2
So 24292-60-2 is a valid CAS Registry Number.
InChI:InChI=1/C21H28N7O17P3.2Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;/h1-4,7-8,10-11,13-16,20-21,29-31H,5-6H2,(H7-,22,23,24,25,32,33,34,35,36,37,38,39);;/q;2*+1/p-2/t10-,11-,13-,14-,15-,16-,20?,21-;;/m1../s1