24331-97-3

Basic information

• Product Name: 1-methyl-1H-pyrrolo<3,2-c>pyridine
• CAS NO: 24331-97-3
• Molecular Weight: 132.165
• Mol File: 24331-97-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-methyl-1H-pyrrolo<3,2-c>pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl-1H-pyrrolo<3,2-c>pyridine(24331-97-3)
• EPA Substance Registry System: 1-methyl-1H-pyrrolo<3,2-c>pyridine(24331-97-3)

Safety Data

• Hazardous Substances Data: 24331-97-3(Hazardous Substances Data)

Usage

Type

Heterocyclic compound
Consists of multiple rings with at least one ring containing heteroatoms

Derivative

Pyridine
A six-membered aromatic ring with one nitrogen atom

Physical state

Colorless liquid

Odor

Distinct

Usage

Building block in the synthesis of various organic compounds
Acts as a precursor or intermediate in the creation of other complex molecules

Pharmaceutical applications

Some pharmaceutical uses
May have potential therapeutic effects or properties

Coordination chemistry

Studied for its potential as a ligand
Can bind to metal ions to form coordination complexes

Organic synthesis

Used in organic synthesis processes
Can be used as a reactant or catalyst in the formation of other organic compounds

Flammability

Highly flammable liquid
Requires careful handling in laboratory settings to avoid fire hazards

Upstream product

• 27382-01-0 1-methyl-4-chloro-1H-pyrrolo<3,2-c>pyridine 
• 271-34-1 5-azaindole 
• 77-78-1 dimethyl sulfate 
• 74-88-4 methyl iodide 

Downstream Products

• 119910-38-2 3-formyl-1-methyl-1H-pyrrolo<3,2-c>pyridine 

Relevant articles and documents

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Synthesis and cytotoxic activity of 3-[2-(1H-Indol-3-yl)-1,3-thiazol-4-yl]-1H-pyrrolo[3,2-c]pyridine hydrobromides, analogues of the marine alkaloid nortopsentin

A new series of thiazole nortopsentin analogues with a 5-azaindole moiety was conveniently synthesized in good to excellent yields by an Hantzsch reaction between thioamides and α-bromoacetyl compounds. The cytotoxic activity of the new derivatives was tested against different human tumor cell lines of the NCI full panel. All tested compounds were active against all of the investigated cell lines showing GI50 values from micro to submicromolar levels. Some of the new analogues exhibited good selectivities against different NCI sub-panels.

4-Substituted-1-methyl-1H-pyrrolopyridines

The synthesis of a series of 4-substituted 1-methyl-1H-pyrrolopyridines is described based on transformations of 4-methyl and 4-chloro analogues.Reactivities of the latter compounds proved less than those of corresponding α-substituted pyridines, but pressure methods allowed isolation of the 4-amino and other amine derivatives in good yield.Under Mannich conditions both 4-methyl and 4-chloro derivatives were converted to bis methanes.