24343-32-6Relevant articles and documents
Synthesis of β-phthalimido-alcohols via regioselective ring opening of epoxide by using reusable basic magnetic nano particles and their biological investigation
Zolfigol, Mohammad Ali,Moosavi-Zare, Ahmad Reza,Zarei, Mahmoud,Zare, Abdolkarim,Noroozizadeh, Ehsan,Karamian, Roya,Asadbegy, Mostafa
, p. 62460 - 62466 (2016/07/14)
In this work, tetra butyl ammonium hydroxide ([Bu4N]OH) and magnetic nano particles (Fe3O4@SiO2@CH2)3NH2) were introduced as efficient catalysts for the regioselective ring openi
An expedient chemo-enzymatic method for the synthesis of optically active masked 1,2-amino alcohols
Gupta, Pankaj,Taneja, Subhash C.,Shah, Bhahwal A.,Mukherjee, Debaraj,Parshad, Rajinder,Chimni, Swapandeep S.,Qazi, Ghulam N.
, p. 1898 - 1903 (2008/12/22)
The expedient synthesis of enantiopure masked 1,2-amino alcohols (ee >99%) including their alkyl substituted analogues has been achieved by the regioselective ring opening of epoxides using phthalimide, followed by highly efficient kinetic resolution under mild and environmentally friendly conditions. The addition of co-solvents during kinetic resolution significantly improved the enantioselectivity with reduction in time.