243666-11-7

Basic information

• Product Name: 4-AMINO-7-(TRIFLUOROMETHYL)QUINOLINE
• Synonyms: AKOS BBS-00002795;7-TRIFLUOROMETHYL-QUINOLIN-4-YLAMINE;4-AMINO-7-TRIFLUOROMETHOXYLQUINOLINE;4-AMINO-7-(TRIFLUOROMETHYL)QUINOLINE;BUTTPARK 11\01-34;7-(trifluoroMethyl)quinolin-4-aMine
• CAS NO: 243666-11-7
• Molecular Formula: C₁₀H₇F₃N₂
• Molecular Weight: 212.17
• Product Categories: NULL
• Mol File: 243666-11-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 329.7 °C at 760 mmHg
• Flash Point: 153.2 °C
• Appearance: /
• Density: 1.390
• Vapor Pressure: 0.000175mmHg at 25°C
• Refractive Index: 1.588
• PKA: 6.68±0.50(Predicted)
• CAS DataBase Reference: 4-AMINO-7-(TRIFLUOROMETHYL)QUINOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMINO-7-(TRIFLUOROMETHYL)QUINOLINE(243666-11-7)
• EPA Substance Registry System: 4-AMINO-7-(TRIFLUOROMETHYL)QUINOLINE(243666-11-7)

Safety Data

• Hazard Codes: Xi,T
• Statements: 25-36
• Safety Statements: 26-45
• Hazardous Substances Data: 243666-11-7(Hazardous Substances Data)

Usage

General Description

4-Amino-7-(trifluoromethyl)quinoline is a chemical compound that belongs to the class of organic compounds known as quinolines, which possess a structure derived from benzopyridine. Its chemical formula is C10H7F3N2. This substance is characterized by having a quinoline ring system substituted at the 4th and 7th positions by an amino group and a trifluoromethyl group, respectively. The presence of the trifluoromethyl group provides the molecule with unique chemical and biological properties, making it a potential candidate for use in pharmaceutical and agrochemical applications. Although more research is needed, compounds like this one are often investigated for their potential therapeutic value.

InChI:InChI=1/C10H7F3N2/c11-10(12,13)6-1-2-7-8(14)3-4-15-9(7)5-6/h1-5H,(H2,14,15)

Upstream product

• 346-55-4 4-chloro-7-trifluoromethyl quinoline 
• 74227-77-3 4-azido-7-(trifluoromethyl)quinoline 
• 1582788-19-9 C₁₀H₅F₃IN 

Downstream Products

• 71079-89-5 N-tert-butyl-N'-thiazol-2-yl-N''-(7-trifluoromethyl-quinolin-4-yl)-guanidine 

Relevant articles and documents

In situ generation of ammonia for the copper-catalyzed synthesis of primary aminoquinolines

The synthesis of primary aminoquinolines from iodoquinolines was carried out in the presence of copper(i) iodide and formamide as the solvent and source of ammonia generated in situ. The reaction proceeded under mild conditions within a few hours and was applicable to various iodoquinolines.

QUINOLINE COMPOUNDS AND THEIR USES

The present invention provides quinoline compounds that inhibit the IgE receptor signaling cascade that leads to the release of chemical mediators, intermediates and methods of synthesizing the compounds and methods of using the compounds in a variety of contexts, including in the treatment and prevention of diseases characterized by, caused by or associated with the release of chemical mediators via degranulation and other processes effected by activation of the IgE receptor signaling cascade.