2437-43-6 Usage
Description
1-(3-methylphenyl)-1H-pyrrole, also known as 3-methyl-1-phenyl-1H-pyrrole, is a heterocyclic compound characterized by a five-membered ring with four carbon atoms and one nitrogen atom. It is recognized for its molecular formula C11H11N and a molecular weight of 157.21 g/mol. This versatile chemical is widely utilized in the scientific and industrial sectors, particularly in organic chemistry and pharmaceutical development.
Uses
Used in Organic Chemistry:
1-(3-methylphenyl)-1H-pyrrole is used as a building block for the synthesis of various pharmaceuticals and agrochemicals. Its unique structure and properties make it a valuable component in the creation of a diverse range of compounds with potential applications in medicine and agriculture.
Used in Cancer Research:
In the field of cancer research, 1-(3-methylphenyl)-1H-pyrrole has demonstrated potential therapeutic properties. It is being explored for its ability to target and disrupt specific biological pathways involved in cancer cell growth and proliferation, offering a promising avenue for the development of novel cancer treatments.
Used in Pharmaceutical Development:
1-(3-methylphenyl)-1H-pyrrole is also utilized in the development of new pharmaceuticals. Its incorporation into drug molecules can enhance their efficacy, selectivity, and overall therapeutic potential, contributing to the advancement of innovative treatments for various diseases and conditions.
Used in Agrochemicals:
In the agrochemical industry, 1-(3-methylphenyl)-1H-pyrrole serves as a key component in the synthesis of compounds with pesticidal, herbicidal, and fungicidal properties. Its application in this field helps to develop more effective and targeted agrochemicals, aiming to improve crop protection and yield while minimizing environmental impact.
Check Digit Verification of cas no
The CAS Registry Mumber 2437-43-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,4,3 and 7 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 2437-43:
(6*2)+(5*4)+(4*3)+(3*7)+(2*4)+(1*3)=76
76 % 10 = 6
So 2437-43-6 is a valid CAS Registry Number.
2437-43-6Relevant articles and documents
A solvent-free manganese(II) -catalyzed Clauson-Kaas protocol for the synthesis of N-aryl pyrroles under microwave irradiation
Rohit, Kizhakkekuttu Radhakrishnan,Meera, Gopinadh,Anilkumar, Gopinathan
supporting information, p. 194 - 200 (2021/10/12)
The first manganese-catalyzed modified Clauson-Kaas reaction for N-substituted pyrrole synthesis using 2,5-dimethoxytetrahydrofuran with variously substituted aromatic amines has been developed (up to 89% yield). This interesting neat strategy is free from additives including co-catalysts, ligands, and acids. Relatively low cost, environmentally benign, and handy Mn(NO3)2·4H2O is employed as the catalyst under microwave conditions with a very short reaction time (20?min). The above qualities attest to the green nature of this reaction.
Lactam derivatives and preparation method and application thereof
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Paragraph 0048-0052; 0076; 0083, (2020/02/10)
The invention relates to lactam derivatives and a preparation method and application thereof. Compared with the prior art, the invention provides lactam compounds with a novel structure. The compoundsand compositions thereof have remarkable activity in inhibition of the proliferation of cancer cells (including, but not limited to, the liver cancer cell line HepG2 and the lung cancer cell line A549), and the activity of multiple compounds is in the same order of magnitude as the activity of the commercial drug adriamycin or superior to the activity of adriamycin. The compounds of the inventioncan be prepared from N-substituted pyrrole compounds through a reaction, and the preparation method is convenient, rapid and efficient.
Natural polynite promote nitrogen heterocyclic compound N-arylation of the method
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Paragraph 0011, (2016/10/31)
The invention discloses a method of promoting N-arylation of nitrogen heterocyclic compounds by natural montmorillonite. The natural montmorillonite is adopted as a promoter and cuprous iodide or copper acetate is adopted as a catalyst, and under alkaline
