2437-88-9

Basic information

• Product Name: phloroglucinol triethyl ether
• Synonyms: phloroglucinol triethyl ether;1,3,5-Triethoxybenzene
• CAS NO: 2437-88-9
• Molecular Formula: C₁₂H₁₈O₃
• Molecular Weight: 210.2695
• Mol File: 2437-88-9.mol
• Article Data: 5

Chemical Properties

• Melting Point: 43.5°C
• Boiling Point: 309.8°C (rough estimate)
• Flash Point: 102.3°C
• Appearance: /
• Density: 1.0733 (rough estimate)
• Vapor Pressure: 0.00138mmHg at 25°C
• Refractive Index: 1.5040 (estimate)
• CAS DataBase Reference: phloroglucinol triethyl ether(CAS DataBase Reference)
• NIST Chemistry Reference: phloroglucinol triethyl ether(2437-88-9)
• EPA Substance Registry System: phloroglucinol triethyl ether(2437-88-9)

Safety Data

• Hazardous Substances Data: 2437-88-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H18O3/c1-4-13-10-7-11(14-5-2)9-12(8-10)15-6-3/h7-9H,4-6H2,1-3H3

Upstream product

• 64-67-5 diethyl sulfate 
• 108-73-6 3,5-dihydroxyphenol 
• 408317-31-7 cyclohexane-1,3,5-trione-tris-diethylacetal 
• 67-64-1 acetone 
• 927-80-0 1-ethoxyacetylene 
• 74-96-4 ethyl bromide 
• 10373-41-8 3,5-diethoxyphenol 
• 124-38-9 carbon dioxide 
• 64-17-5 ethanol 
• 75-03-6 ethyl iodide 
• 7664-93-9 sulfuric acid 
• 83-30-7 acide 2,4,6-trihydroxybenzoique 
• 117029-67-1 2,4,6-triethoxybenzoic acid 

Downstream Products

• 59652-88-9 2,4,6-triethoxy-benzaldehyde 
• 480439-37-0 1-(2,4,6-triethoxy-phenyl)-ethanone 
• 1407168-48-2 ethyl 3-oxo-2-(2,4,6-triethoxybenzyl)butanoate 

Relevant articles and documents

Transition metal-free protodecarboxylation of electron rich aromatic acids under mild conditions

A mild and practical method for the transition metal-free protodecarboxylation of aromatic acids using readily available and safe sodium persulfate as initiator was described. This environment-friendly decarboxylation approach was performed at 60 °C in ethanol and could easily scale up to the gram level with a good yield. In Particular, the tandem reactions of decarboxylation and halogenation were achieved by the addition of the corresponding halogenating reagents to the reaction system.

SYNTHESIS OF PHLOROGLUCINOL TRIALKYL ETHERS

The alkylation of phloroglucinol dialkyl ethers with alcohols or alkyl halides leads, depending on the reaction conditions, either to products of O- or C- alkylation, or to C,O-alkylation products.Reaction conditions were found which enable us to obtain pure phloroglucinol trialkyl ethers.A convenient preparative method for the synthesis of phloroglucinol trialkyl ethers consists in the alkylation of phloroglucinol dialkyl ethers in a two-phase system in presence of phase-transfer catalysts.

Process for preparing a S-trialkoxy benzene

A 1,3,5-trialkoxy benzene having 1-2 carbon atoms in each of the alkoxy-groups is prepared at high overall yields, with minimal formation of hazardous or polluting by-products, by reacting 1,3,5-tribromo benzene with an alkalimetal alcoholate having 1-3 carbon atoms in the molecule in the presence of a copper salt, e.g. cuprous iodide or cupric chloride, and an aprotic solvent such as e.g. dimethylformamide. The product is readily recovered from the reaction mixture in an overall yield as high as 90%.