24374-77-4

Basic information

• Product Name: 1-(1H-benzimidazol-2-yl)-3-butylurea
• Synonyms: 1-(1H-Benzimidazol-2-yl)-3-butylurea; urea, N-1H-benzimidazol-2-yl-N'-butyl-
• CAS NO: 24374-77-4
• Molecular Formula: C₁₂H₁₆N₄O
• Molecular Weight: 232.2816
• Mol File: 24374-77-4.mol
• Article Data: 1

Chemical Properties

• Density: 1.245g/cm³
• Refractive Index: 1.654
• CAS DataBase Reference: 1-(1H-benzimidazol-2-yl)-3-butylurea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1H-benzimidazol-2-yl)-3-butylurea(24374-77-4)
• EPA Substance Registry System: 1-(1H-benzimidazol-2-yl)-3-butylurea(24374-77-4)

Safety Data

• Hazardous Substances Data: 24374-77-4(Hazardous Substances Data)

Usage

Description

1-(1H-benzimidazol-2-yl)-3-butylurea, a chemical compound with the molecular formula C13H18N4O, is a derivative of benzimidazole and urea. It is recognized for its potential in medicinal chemistry due to its ability to inhibit protein tyrosine phosphatases, enzymes that play a crucial role in regulating cell growth and differentiation.

Uses

Used in Cancer Treatment:
1-(1H-benzimidazol-2-yl)-3-butylurea is used as an inhibitor for protein tyrosine phosphatases in the pharmaceutical industry. Its application is aimed at preventing tumor growth by targeting and inhibiting the activity of these enzymes, which are often dysregulated in cancer cells, contributing to uncontrolled cell proliferation and tumor progression.
Used in Autoimmune Disease Treatment:
In the medical field, 1-(1H-benzimidazol-2-yl)-3-butylurea is also being explored as a potential therapeutic agent for autoimmune diseases. Its ability to modulate the activity of protein tyrosine phosphatases may help in regulating the immune system and reducing the severity of autoimmune conditions.
Used in Diabetes Treatment:
1-(1H-benzimidazol-2-yl)-3-butylurea is being investigated for its potential use in treating diabetes. 1-(1H-benzimidazol-2-yl)-3-butylurea's impact on protein tyrosine phosphatases, which are involved in insulin signaling pathways, may offer a new approach to managing blood sugar levels and improving the treatment of diabetes.
Overall, 1-(1H-benzimidazol-2-yl)-3-butylurea is a promising compound with various applications in the medical and pharmaceutical industries, primarily due to its ability to inhibit protein tyrosine phosphatases, which are implicated in cancer, autoimmune diseases, and diabetes.