24393-43-9Relevant articles and documents
Imidazolium chloride immobilized SBA-15 as a heterogenized organocatalyst for solvent free Knoevenagel condensation using microwave
Parvin, Mst. Nargis,Jin, Hua,Ansari, Mohd. Bismillah,Oh, Soon-Moon,Park, Sang-Eon
, p. 205 - 212 (2012)
Heterogeneous organocatalyst, 1-methyl-3-[(3-triethoxysilyl) propyl] imidazolium chloride [MTESPImCl] immobilized SBA-15 (ILS) was synthesized by co-condensation method using microwave irradiation in which 1-methylimidazole (Im) was modified by organosila
Organophosphonate-Functionalized Telluromolybdate Containing a [TeMo10O37]10-Building Block and Its Catalytic Efficiency for Knoevenagel Condensation
Kong, Hui,Xu, Baijie,Zhen, Jing,Liu, Siyu,Li, Keli,Ma, Pengtao,Wang, Jingping,Niu, Jingyang
, p. 14872 - 14879 (2021/10/01)
A novel organodiphosphonate-based telluromolybdate cluster, (NH4)6Na3H13[TeMo10O37(CoMo2O6L)4]·11H2O [1; L = (O3P)2C(O)(CH2)3NH2], has been successfully synthesized by a simple one-pot aqueous reaction. Intriguingly, the [TeMo10O37]10- subunit with tetrah
Water mediated procedure for preparation of stereoselective oximes as inhibitors of MRCK kinase
Luqman, Suaib,Misra, Krishna,Pandey, Jyoti,Shrivash, Manoj Kumar,Shukla, Akhilesh Kumar,Singh, Shilipi
, (2020/07/08)
Stereoselective aldoximes, preferably Z form have been obtained from α-cyano substituted carbonyl conjugated alkenes. This reaction occurs through Michael addition type reaction followed by retro-Knoevenagel reaction without transition-metal catalysis via C–C bond cleavage. These oximes are evaluated against cancer cell lines employing mechanistic study. Two oximes showed significant cytotoxic activity, which through in silico studies were found to inhibit MRCK Kinase, responsible for metastatic spread of cancer mortality.