244233-79-2

Basic information

• Product Name: 1H-Pyrazol-5-amine, 1-(5-chloro-2-nitrophenyl)-3-(3-thienyl)-
• CAS NO: 244233-79-2
• Molecular Formula: C13H9ClN4O2S
• Molecular Weight: 320.759
• Mol File: 244233-79-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-Pyrazol-5-amine, 1-(5-chloro-2-nitrophenyl)-3-(3-thienyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazol-5-amine, 1-(5-chloro-2-nitrophenyl)-3-(3-thienyl)-(244233-79-2)
• EPA Substance Registry System: 1H-Pyrazol-5-amine, 1-(5-chloro-2-nitrophenyl)-3-(3-thienyl)-(244233-79-2)

Safety Data

• Hazardous Substances Data: 244233-79-2(Hazardous Substances Data)

Upstream product

• 69879-30-7 2-(thiophene-3-carbonyl)acetonitrile 
• 1966-16-1 5-chloro-2-nitrophenylhydrazine 

Relevant articles and documents

Benzodiazepine receptor ligands III. Synthesis and biological evaluation of 2- and/or 3-substituted pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxides

A new series of 2- and/or 3-substituted pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxides and their 8-chloro derivatives were synthesized, and their benzodiazepine receptor (BZR) affinities were evaluated in vitro in comparison to lead compound 3-ethoxycarbonyl-8-chloropyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide (29) [1,2]. None of the new compounds showed significant affinity for BZR. On the basis of a pharmacophore/receptor model suggested for lead compound 29, some hypotheses to explain the inactivity of new derivatives are discussed.