244240-03-7Relevant articles and documents
Synthesis of optically active 1,4-benzoxazinones and 1,5- benzoxazepinones by regiocontrolled ring transformations of oxirane carboxylic acids and esters with aromatic o-hydroxyarylamines
Woydowski, Karsten,Liebscher, Juergen
, p. 9205 - 9220 (2007/10/03)
Enantiopure diethyl oxirane dicarboxylate 1 reacts with o-aminophenols 2 either to 1,4-benzoxazin-2-ones 5 or to the 1,5-benzoxazepin-2-one 4 while a condensed 1,4-oxazin-3-one 6 was obtained with 2-amino-3-hydroxypyridine. On the other hand optical activ