2443-71-2

Basic information

• Product Name: L-Valine, N-[(phenylmethoxy)carbonyl]-, hydrazide
• CAS NO: 2443-71-2
• Molecular Formula: C13H19N3O3
• Molecular Weight: 265.312
• Mol File: 2443-71-2.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: L-Valine, N-[(phenylmethoxy)carbonyl]-, hydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: L-Valine, N-[(phenylmethoxy)carbonyl]-, hydrazide(2443-71-2)
• EPA Substance Registry System: L-Valine, N-[(phenylmethoxy)carbonyl]-, hydrazide(2443-71-2)

Safety Data

• Hazardous Substances Data: 2443-71-2(Hazardous Substances Data)

Upstream product

• 1149-26-4 N-benzyloxycarbonylvaline 
• 134306-34-6 N-(Benzyloxycarbonyl)valine methyl ester 
• 119706-21-7 2-(benzhydrylamino)-2-oxoethyl ((benzyloxy)carbonyl)-L-valinate 
• 5276-76-6 4-nitrobenzyl ((benzyloxy)carbonyl)-L-valinate 
• 238400-05-0 2-hydroxyethyl ((benzyloxy)carbonyl)-L-valinate 
• 73504-31-1 benzyloxycarbonylamino 3-butyric acid benzyl ester 
• 42417-65-2 Z-MeVal-OH 
• 6306-52-1 L-valine methylester hydrochloride 
• 17498-50-9 L-valine hydrochloride 
• 67436-18-4 N-benzyloxycarbonyl-S-valine methyl ester 
• 501-53-1 benzyl chloroformate 
• 1149-26-4 (S)-N-(benzyloxycarbonyl)valine 
• 72-18-4 L-valine 
• 4070-48-8 L-Valine methyl ester 

Downstream Products

• 4864-40-8 N^δ-benzyloxycarbonyl-N^α-(N-benzyloxycarbonyl-valyl)-ornithine methyl ester 
• 1352815-88-3 C₂₅H₂₃N₃O₅ 
• 41041-70-7 Benzyloxycarbonyl-L-alanyl-L-leucinethylester 
• 93788-22-8 (R,R)-bis(N-benzyloxycarbonylvalyl)diaza-18-crown-6 

Relevant articles and documents

An Atom-Economic Inverse Solid-Phase Peptide Synthesis Using Bn or BcM Esters of Amino Acids

An atom-economic N-to-C-directed solid-phase peptide synthesis is reported that uses benzyl (Bn) or (benzhydryl-carbamoyl)-methyl (BcM) esters of amino acids as the building blocks, which facilitate efficient hydrazinolysis, convenient conversion to acyl azide, and robust amidation with the next amino acid ester. This method is free of coupling reagents and free of protection on the side-chain OH, CO2H, CONH2, etc., therefore exhibiting a significantly improved atom economy compared to those of BOC- or Fmoc-based C-to-N-directed approaches.

FUMAGILLOL COMPOUNDS AND METHODS OF MAKING AND USING SAME

Disclosed herein, in part, are fumagillol compounds and methods of use in treating medical disorders, such as obesity. Pharmaceutical compositions and methods of making fumagillol compounds are provided. The compounds are contemplated to have activity against methionyl aminopeptidase 2.

Carbonylhydrazide-based molecular tongs inhibit wild-type and mutated HIV-1 protease dimerization

We have designed and synthesized new molecular tongs based on a rigid naphthalene scaffold and evaluated their antidimer activity on HIV-1 protease (PR). We inserted carbonylhydrazide and oligohydrazide (azatide) fragments into their peptidomimetic arms t