24430-27-1

Basic information

• Product Name: 3-BROMO-2-NITROTHIOPHENE
• Synonyms: 2-Nitro-3-bromothiophene;Thiophene,3-broMo-2-nitro-
• CAS NO: 24430-27-1
• Molecular Formula: C₄H₂BrNO₂S
• Molecular Weight: 208.04
• Product Categories: Heterocycle-oher series
• Mol File: 24430-27-1.mol
• Article Data: 3

Chemical Properties

• Melting Point: 79-81 °C(Solv: hexane (110-54-3))
• Boiling Point: 228.6 °C at 760 mmHg
• Flash Point: 92.1 °C
• Appearance: /
• Density: 1.945 g/cm³
• Vapor Pressure: 0.11mmHg at 25°C
• Refractive Index: 1.647
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 3-BROMO-2-NITROTHIOPHENE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-2-NITROTHIOPHENE(24430-27-1)
• EPA Substance Registry System: 3-BROMO-2-NITROTHIOPHENE(24430-27-1)

Safety Data

• Hazardous Substances Data: 24430-27-1(Hazardous Substances Data)

Usage

General Description

3-Bromo-2-nitrothiophene is a chemical compound with the molecular formula C4H2BrNO2S. It is a yellow solid that is used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. 3-BROMO-2-NITROTHIOPHENE is known for its reactivity and is commonly used in the synthesis of heterocyclic compounds, specifically thieno[2,3-b]pyridines, which have potential applications as antimicrobial, antiviral, and anticancer agents. Additionally, 3-Bromo-2-nitrothiophene is also used in the preparation of dyes and pigments. It is important to handle this compound with caution, as it is classified as a hazardous substance and can cause irritation to the eyes, skin, and respiratory system upon exposure.

InChI:InChI=1/C4H2BrNO2S/c5-3-1-2-9-4(3)6(7)8/h1-2H

Upstream product

• 872-31-1 3-Bromothiophene 

Downstream Products

• 122777-92-8 (2-Nitro-thiophen-3-yl)-(2-pyrrolidin-1-yl-ethyl)-amine; hydrochloride 
• 122777-90-6 (2-Morpholin-4-yl-ethyl)-(2-nitro-thiophen-3-yl)-amine; hydrochloride 
• 122777-91-7 (3-Morpholin-4-yl-propyl)-(2-nitro-thiophen-3-yl)-amine; hydrochloride 
• 122777-62-2 Hexyl-(2-nitro-thiophen-3-yl)-amine 
• 93102-58-0 2-nitro-3-phenoxythophene 
• 93102-38-6 3-<2'-formylphenoxy>-2-nitrothiophene 
• 93102-56-8 ethyl 2-(2'-nitro-3'-thienyloxy)benzoate 
• 122777-61-1 Butyl-(2-nitro-thiophen-3-yl)-amine 
• 51679-11-9 2-nitro-3-thienyl-4'-nitrophenylsulfide 
• 52003-20-0 3-amino-2-nitrothiophene 
• 30989-91-4 2,2'-dinitro-3,3'-dithienylsulfide 
• 220965-65-1 ethyl α-(2-nitro-3-thienylthio)-4-chlorophenylacetate 
• 220965-59-3 3-(4-chlorobenzylthio)-2-nitrothiophene 
• 85598-50-1 2-Nitro-3-cyano-thiophen 

Relevant articles and documents

AROMATIC 2-NITROSULFONYL FLUORIDE ANTIBIOTICS AND METHODS OF USE THEREOF

Aspects of the present disclosure include antibacterial aromatic sulfonyl fluoride agents. The subject aromatic sulfonyl fluoride agents have a pharmacophore that can provide for potent antibacterial activity. The subject agents are compounds including an

Heterocyclic-ring condensed benzothiazine compound

The invention provides a novel heterocyclic ring condensed benzothiazine compound which is effective for prevention or remedy of disease, in which histamine, leukotriene and the like participate. The heterocyclic ring condensed benzothiazine compound of the present invention or a pharmacologically acceptable salt thereof is effective for prevention or remedy of disease, in which a chemical mediator, such as histamine, leukotriene and the like, participate, for example, asthma, allergic coryza, atopic dermatitis, hives, hay fever, gastrointestinal allergy, food allergy and the like. Further, the heterocyclic ring condensed benzothiazine compound of the present invention, its pharmacologically acceptable salt or hydrates thereof is represented by the following formula: In the formula, the ring Het represents an unsaturated heterocyclic ring; R1and R2are the same as or different from each other, and each represents halogen atom, a lower alkyl group that may be substituted with a halogen atom, a lower alkoxy group that may be substituted with a halogen atom, a lower alkyl lower alkoxy group, cyano group; D represents a lower alkylene group and the like that may have a substituent; Q represents, for example, the formula —NR20R2(in the formula, R20and R21are the same as or different from each other, and each represents hydrogen atom, a lower alkyl group that may be substituted with a halogen atom, an aryl group that may have a substituent, an arylalkyl group that may have a substituent, a heteroaryl group that may have a substituent or a heteroarylalkyl group that may have a substituent, or R20and R21may form a 3- to 8-membered ring along with the nitrogen atom to which they are bound); and x represents an integer of from 1 to 2.