244308-15-4

Basic information

• Product Name: 1-(4,4-dimethoxybutyl)-4,4-dimethylcyclopent-2-en-1-ol
• Synonyms: 1-(4,4-dimethoxybutyl)-4,4-dimethylcyclopent-2-en-1-ol
• CAS NO: 244308-15-4
• Molecular Weight: 228.332
• Mol File: 244308-15-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(4,4-dimethoxybutyl)-4,4-dimethylcyclopent-2-en-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4,4-dimethoxybutyl)-4,4-dimethylcyclopent-2-en-1-ol(244308-15-4)
• EPA Substance Registry System: 1-(4,4-dimethoxybutyl)-4,4-dimethylcyclopent-2-en-1-ol(244308-15-4)

Safety Data

• Hazardous Substances Data: 244308-15-4(Hazardous Substances Data)

Upstream product

• 22748-16-9 4,4-dimethylcyclopent-2-ene-1-one 
• 24157-02-6 4-bromo-1,1-dimethoxybutane 

Relevant articles and documents

Nickel-catalyzed cyclizations of enoate equivalents: Application to the synthesis of angular triquinanes

Unsaturated acyloxazolidinones and α'-silyloxy enones were found to be effective substrates in nickel-catalyzed organozinc-promoted cyclizations. Both groups served as convenient enoate equivalents, whereas methyl enoates themselves were inefficient substrates. A five-step procedure for the conversion of dimethylcyclopentenone into a highly functionalized angular triquinane was developed utilizing this observation. The key step of the procedure involves a nickel-catalyzed reductive cyclization/Dieckmann condensation sequence involving a cyclic enone tethered to an unsaturated acyloxazolidinone or α'-silyloxy enone. The method was applied in a formal synthesis of pentalenene, pentalenic acid, and deoxypentalenic acid.