244638-20-8

Basic information

• Product Name: 2-(4-chlorophenyl)-7-(3-cyanopropyl)-2,5-dihydro-6-methylpyrazolo[4,3-c]pyridin-3-one
• Synonyms: 2-(4-chlorophenyl)-7-(3-cyanopropyl)-2,5-dihydro-6-methylpyrazolo[4,3-c]pyridin-3-one
• CAS NO: 244638-20-8
• Molecular Weight: 326.785
• Mol File: 244638-20-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(4-chlorophenyl)-7-(3-cyanopropyl)-2,5-dihydro-6-methylpyrazolo[4,3-c]pyridin-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-chlorophenyl)-7-(3-cyanopropyl)-2,5-dihydro-6-methylpyrazolo[4,3-c]pyridin-3-one(244638-20-8)
• EPA Substance Registry System: 2-(4-chlorophenyl)-7-(3-cyanopropyl)-2,5-dihydro-6-methylpyrazolo[4,3-c]pyridin-3-one(244638-20-8)

Safety Data

• Hazardous Substances Data: 244638-20-8(Hazardous Substances Data)

Upstream product

• 244637-95-4 2-(4-chlorophenyl)-2,5-dihydro-7-iodo-6-methylpyrazolo[4,3-c]pyridin-3-one 
• 6727-73-7 4-iodobutyronitrile 
• 181277-21-4 3-(dimethylaminomethine)-4-oxo-6-methyl-2-pyrone 
• 67367-33-3 4-hydroxy-6-methylnicotinic acid 
• 675-10-5 4-hydroxy-6-methyl-2-pyron 
• 868363-06-8 4-hydroxy-5-iodo-6-methyl-nicotinic acid 
• 868363-07-9 Methyl 4-chloro-3-iodo-2-methyl-5-pyridinecarboxylate 

Relevant articles and documents

Pyrazolopyridinones as functionally selective GABAA ligands

2,5-Dihydro-3H-pyrazolo[4,3-c]pyridin-3-ones are GABAA receptor benzodiazepine binding site ligands, which can exhibit functional selectivity for the α3 subtype over the α1 subtype. SAR studies to optimize this functional