244759-53-3

Basic information

• Product Name: 5,6-DIMETHYL-2-STYRYL-1H-1,3-BENZIMIDAZOLE
• Synonyms: 5,6-DIMETHYL-2-STYRYL-1H-1,3-BENZIMIDAZOLE;5,6-dimethyl-2-[(E)-2-phenylethenyl]-1H-1,3-benzodiazole
• CAS NO: 244759-53-3
• Molecular Formula: C17H16N2
• Molecular Weight: 248.32
• Mol File: 244759-53-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5,6-DIMETHYL-2-STYRYL-1H-1,3-BENZIMIDAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6-DIMETHYL-2-STYRYL-1H-1,3-BENZIMIDAZOLE(244759-53-3)
• EPA Substance Registry System: 5,6-DIMETHYL-2-STYRYL-1H-1,3-BENZIMIDAZOLE(244759-53-3)

Safety Data

• Hazardous Substances Data: 244759-53-3(Hazardous Substances Data)

Upstream product

• 3363-56-2 2,5,6-trimethylbenzimidazole 
• 14371-10-9 (E)-3-phenylpropenal 
• 3171-45-7 4,5-dimethyl-1,2-phenylenediamine 
• 6972-71-0 4,5-dimethyl-2-nitrobenzenamine 
• 104-55-2 3-phenyl-propenal 

Relevant articles and documents

Benzimidazole compounds having activity against hepatitis B viruses and antibacterial activity, and a synthetic method and application thereof

Benzimidazole compounds having activity against hepatitis B viruses and antibacterial activity, and a synthetic method and application thereof are disclosed. Structures of the compounds are shown as ageneral formula (I) in the description. The synthetic method of the compounds, and the application of the compounds in preparation of medicines against hepatitis B viruses are also disclosed. The compounds have certain anti-HBV activity and antibacterial activity, and the activity against hepatitis B viruses of the compounds is equivalent to that of tenofovir that is a clinical anti-HBV medicine.Antibacterial activity screening shows that the compounds have good suppressing activity for Staphylococcus aureus. In the fields of compound structures, synthetic methods and bioactivity, the compounds have significant scientific significance and application prospects for developing novel anti(hepatitis B) medicines of a novel structure type and antibacterial medicines.

Benzimidazole cyclooxygenase-2 inhibitors

This invention provides a compound of the following formula: or the pharmaceutically acceptable salts thereof, wherein Ar is heteroaryl; X1and X2are independently selected from halo, C1-C4alkyl, hydroxy, C1-C4alkoxy, amino, C1-C4alkanoyl, carboxy, carbamoyl, cyano, nitro, mercapto, (C1-C4alkyl)thio, (C1-C4alkyl)sulfinyl, (C1-C4alkyl)sulfonyl, aminosulfonyl, or the like; R1is selected from hydrogen, straight or branched C1-C4alkyl, C3-C8cycloalkyl, C4-C8cycloalkenyl, phenyl , heteroaryl and the like; R2and R3are independently selected from hydrogen, halo, C1-C4alkyl, phenyl and the like; or R1and R2can form, together with the carbon atom to which they are attached, a C5-C7cycloalkyl ring; and m and n are independently 0, 1, 2 or 3. These compounds and pharmaceutical compositions containing such compounds are useful as analgesics and anti-inflammatory agents.