2448-68-2 Usage
Description
1'-[4-(4-fluorophenyl)-4-oxobutyl][1,4'-bipiperidine]-4'-carboxamide dihydrochloride is a chemical compound with a complex structure, characterized by its off-white to pale yellow solid appearance. It is a hydrochloride resulting from the reaction of the base compound with two moles of hydrogen chloride.
Uses
1. Used in Pharmaceutical Industry:
1'-[4-(4-fluorophenyl)-4-oxobutyl][1,4'-bipiperidine]-4'-carboxamide dihydrochloride is used as an antipsychotic agent for the treatment of various psychiatric disorders. Its application is based on its ability to interact with specific receptors in the brain, such as the human ether-a-go-go-related gene (hERG) channel, which is crucial for the modulation of neuronal excitability and the treatment of psychiatric conditions.
2. Used in Analytical Chemistry:
1'-[4-(4-fluorophenyl)-4-oxobutyl][1,4'-bipiperidine]-4'-carboxamide dihydrochloride is used as an internal standard in liquid chromatography with coulometric detection. Its application is due to its chemical stability and compatibility with the detection method, allowing for accurate quantification of target compounds in various samples.
3. Used in Research and Development:
1'-[4-(4-fluorophenyl)-4-oxobutyl][1,4'-bipiperidine]-4'-carboxamide dihydrochloride is used as an internal standard to spike human colostrum samples for reversed phase liquid chromatography-ultraviolet (LC-UV) analysis. Its application is based on its ability to provide a consistent reference point for the quantification of target compounds in complex biological samples, such as colostrum.
Biochem/physiol Actions
Pipamperone, a butyrophenone derivative is a pharmacological chaperone and is a membrane-permeable dopamine receptor D4 (DRD4) antagonist. The affinity of pipamperone is higher for DRD4 and 5-hydroxytryptamine 2A receptor (5-HT2A) in comparison with DRD2. It may be useful therapeutic in treating behavioral disorders and psychomotor agitation symptoms.
Check Digit Verification of cas no
The CAS Registry Mumber 2448-68-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,4,4 and 8 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 2448-68:
(6*2)+(5*4)+(4*4)+(3*8)+(2*6)+(1*8)=92
92 % 10 = 2
So 2448-68-2 is a valid CAS Registry Number.