245037-12-1

Basic information

• Product Name: N-phenyloxycarbonyl-7-hydroxy-8-azabicyclo[4.3.0]nonane
• Synonyms: N-phenyloxycarbonyl-7-hydroxy-8-azabicyclo[4.3.0]nonane
• CAS NO: 245037-12-1
• Molecular Weight: 261.321
• Mol File: 245037-12-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-phenyloxycarbonyl-7-hydroxy-8-azabicyclo[4.3.0]nonane(CAS DataBase Reference)
• NIST Chemistry Reference: N-phenyloxycarbonyl-7-hydroxy-8-azabicyclo[4.3.0]nonane(245037-12-1)
• EPA Substance Registry System: N-phenyloxycarbonyl-7-hydroxy-8-azabicyclo[4.3.0]nonane(245037-12-1)

Safety Data

• Hazardous Substances Data: 245037-12-1(Hazardous Substances Data)

Upstream product

• 1470-99-1 cis-hexahydroisoindoline 
• 245036-94-6 N-phenyloxycarbonyl-meso-8-azabicyclo[4.3.0]nonane 
• 7506-66-3 cis-hexahydrophthalimide 
• 1469-48-3 cis-1,2,3,6-Tetrahydrophthalimide 

Relevant articles and documents

Asymmetric desymmetrization of meso-pyrrolidine derivatives by enantiotopic selective C-H hydroxylation using (salen)manganese(III) complexes

Chiral (salen)manganese(III) complexes 1 catalyzed the asymmetric desymmetrization of N-protected meso-pyrrolidine derivatives 3, 6-8, 15 and 18 by enantiotopic selective C-H oxidation in the presence of terminal oxidant iodosylbenzene. The oxidation occurred chemoselectively at the carbon α to the nitrogen atom to afford optically active hydroxypyrrolidine derivatives 9, 11, 13, 16, 19 and 21 that were further oxidized to chiral lactams with Jones reagent. The N-protecting groups of the meso-pyrrolidine derivatives have notable effect on the enantioselectivity.