245649-77-8

Basic information

• Product Name: 4-chloro-N-(2-((4-chlorophenyl)thio)phenyl)benzenesulfonamide
• Synonyms: 4-chloro-N-(2-((4-chlorophenyl)thio)phenyl)benzenesulfonamide
• CAS NO: 245649-77-8
• Molecular Weight: 410.345
• Mol File: 245649-77-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-chloro-N-(2-((4-chlorophenyl)thio)phenyl)benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-N-(2-((4-chlorophenyl)thio)phenyl)benzenesulfonamide(245649-77-8)
• EPA Substance Registry System: 4-chloro-N-(2-((4-chlorophenyl)thio)phenyl)benzenesulfonamide(245649-77-8)

Safety Data

• Hazardous Substances Data: 245649-77-8(Hazardous Substances Data)

Upstream product

• 98-60-2 4-chlorobenzenesulfonyl chloride 
• 6764-10-9 4-chlorophenyl 2-nitrophenyl sulfide 
• 14752-66-0 sodium p-chlorobenzenesulphinate 
• 106-54-7 p-Chlorothiophenol 
• 1493-27-2 ortho-nitrofluorobenzene 

Downstream Products

• 245649-78-9 2-(4-Chlorophenylthio)-N-(4-chlorobenzenesulfonyl)-N-(2-dimethylaminoethyl)aniline.HCl 

Relevant articles and documents

Fe-based metal-organic frameworks for the synthesis of N-arylsulfonamides via the reactions of sodium arylsulfinates or arylsulfonyl chlorides with nitroarenes in water

A newly developed chemoselective reaction of sodium arylsulfinates or arylsulfonyl chlorides with nitroarenes has been disclosed. The chemistry, in which non-toxic water and recyclable iron-based metal-organic frameworks are employed as the solvent and catalyst, respectively, provides an efficient approach for the generation of N-arylsulfonamides, which are widely present in biologically active compounds and drugs, rendering this methodology attractive to both synthetic and medicinal chemistry.