24588-58-7

Basic information

• Product Name: Diethyl 3,6-dihydro-2H-pyran-2,2-dicarboxylate
• Synonyms: Diethyl 3,6-dihydro-2H-pyran-2,2-dicarboxylate;3,6-Dihydro-2H-pyran-2,2-dicarboxylic acid diethyl ester;3,6-dihydro-2H-Pyran-2,2-dicarboxylic acid 2,2-diethyl ester
• CAS NO: 24588-58-7
• Molecular Formula: C₁₁H₁₆O₅
• Molecular Weight: 228.24
• Mol File: 24588-58-7.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Diethyl 3,6-dihydro-2H-pyran-2,2-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Diethyl 3,6-dihydro-2H-pyran-2,2-dicarboxylate(24588-58-7)
• EPA Substance Registry System: Diethyl 3,6-dihydro-2H-pyran-2,2-dicarboxylate(24588-58-7)

Safety Data

• Hazardous Substances Data: 24588-58-7(Hazardous Substances Data)

Upstream product

• 106-99-0 buta-1,3-diene 
• 609-09-6 Diethyl ketomalonate 
• 75-03-6 ethyl iodide 
• 105-53-3 diethyl malonate 

Downstream Products

• 85373-58-6 2,2-bishydroxymethyltetrahydropyran 
• 54230-53-4 2,3-O,N-dibenzoyl-1-O-methyl-β,D-ezoaminuroic acid methyl ester 
• 116233-55-7 N-<(R)-1-(p-methoxyphenyl)ethyl>-2,5-dihydro-6H-pyran-6-carboxamide 
• 116233-57-9 4-exo-bromo-6-<(R)-1-(p-methoxyphenyl)ethyl>-6-aza-2-oxabicyclo<3.2.1>octan-7-one 
• 116233-66-0 1-O-methyl-β,D-ezoaminouric acid 
• 116233-68-2 1-O-methyl-β,L-ezoaminouric acid 
• 116233-62-6 6-<(R)-1-(p-methoxyphenyl)ethyl>-6-aza-2-oxabicyclo-<3.2.1>oct-3-en-7-one 
• 116298-50-1 6-<(R)-1-(p-methoxyphenyl)ethyl>-6-aza-2-oxabicyklo-<3.2.1>oct-3-en-7-one 
• 116233-63-7 4-exo-hydroxy-3-endo-methoxy-6-<(R)-1-(p-methoxyphenyl)ethyl>-6-aza-2-oxabicyclo<3.2.1>octan-7-one (L) 
• 116233-63-7 4-exo-hydroxy-3-endo-methoxy-6-<((R)-1-methoxyphenyl)ethyl>-6-aza-2-oxabicyclo<3.2.1>octan-7-one (D) 
• 116233-64-8 4-exo-acetoxy-3-endo-methoxy-6-<(R)-1-(p-methoxyphenyl)ethyl>-6-aza-2-oxabicyclo<3.2.1>octan-7-one (L) 
• 116233-64-8 4-exo-acetoxy-3-endo-methoxy-6-<(R)-1-(p-methoxyphenyl)ethyl>-6-aza-2-oxabicyclo<3.2.1>octan-7-one (D) 

Relevant articles and documents

Formal [5+1] annulation reactions of dielectrophilic peroxides: Facile access to functionalized dihydropyrans

A general [5+1] annulation reaction, which utilized 4-bromo- or 4-mesyloxy-but-2-enyl peroxides as unique five-atom bielectrophilic synthons to participate in the C-C and the subsequent umpolung C-O bond-forming reactions with C1 nucleophiles, has been developed for the facile synthesis of 2,2-disubstituted dihydropyrans in high yields under mild basic conditions. The dihydropyrans, which are readily prepared on a gram scale by this new method, can be flexibly transformed into the biologically important tetrahydropyrans and pyranones in 1-2 steps.

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