246158-05-4Relevant articles and documents
Synthesis of a novel β-turn mimetic and its incorporation in Leu- enkephalin
Kreye, Paul,Kihlberg, Jan
, p. 6113 - 6116 (2007/10/03)
A conformationally restricted β-turn mimetic, in which an ethylene bridge replaces the intramolecular hydrogen bond between residues i and i+3 of β-turns, has been prepared and incorporated in Leu-enkephalin. Amino acids and α-bromoacids were used as building blocks in the synthesis of the mimetic.